Tecnologico de Monterrey, Institute for Obesity Research, Ave. Eugenio Garza Sada 2501, Monterrey, N.L., 64849, Mexico.
Instituto de Productos Lácteos de Asturias-Consejo Superior de Investigaciones Científicas (IPLA-CSIC), Paseo Río Linares s/n, 33300 Villaviciosa, Asturias, Spain.
Food Chem. 2025 Jan 15;463(Pt 1):141123. doi: 10.1016/j.foodchem.2024.141123. Epub 2024 Sep 4.
Milk oligosaccharides are high added value compounds that could be obtained by exploiting cheese whey, a byproduct of dairy industry. The objective was to compare the abundance and diversity of oligosaccharides in whey samples from domestic animals and humans. During fresh cheese making, whey samples were collected and analyzed by untargeted and targeted small molecule analysis using high-resolution mass-spectrometry. A great similarity in the metabolite profile between goat and sheep was observed. Up to 11 oligosaccharides were observed in the sheep whey from those typically found in humans. The concentration of 2'-Fucosyllactose (0.136 ± 0.055 g/L) and 3-Fucosyllactose (0.079 ± 0.009 g/L) were significantly higher (p-value <0.01) in sheep whey, while the concentration of 3'-Sialyllactose (0.826 ± 0.638 g/L) was higher in goat whey. No significant differences were observed between goat and sheep whey for the other oligosaccharides (p-value >0.05). Therefore, sheep and goat whey could become an important source of oligosaccharides through their revalorization.
乳寡糖是高附加值的化合物，可以通过利用奶酪乳清（乳制品工业的副产品）来获得。本研究的目的是比较来自家畜和人类乳清样本中寡糖的丰度和多样性。在新鲜奶酪制作过程中，收集乳清样本，并使用高分辨率质谱进行非靶向和靶向小分子分析。结果表明，山羊和绵羊乳清的代谢物图谱非常相似。在绵羊乳清中发现了 11 种通常在人类中发现的寡糖。2'-岩藻糖基乳糖（0.136±0.055 g/L）和 3-岩藻糖基乳糖（0.079±0.009 g/L）的浓度显著更高（p 值<0.01），而 3'-唾液酸乳糖（0.826±0.638 g/L）在山羊乳清中的浓度更高。其他寡糖在山羊乳清和绵羊乳清之间没有观察到显著差异（p 值>0.05）。因此，绵羊和山羊乳清可以通过再利用成为寡糖的重要来源。
