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阑尾周围炎揭示的隐匿性血吸虫病:一例报告

Hidden schistosomiasis unveiled by appendicular peritonitis: A case report.

作者信息

Limaiem Faten, Zaafouri Montassar, Atallah Aziz

机构信息

University of Tunis El Manar, Faculty of Medicine of Tunis, Tunisia; Pathology Department, Mongi Slim Hospital La Marsa, Tunisia.

University of Tunis El Manar, Faculty of Medicine of Tunis, Tunisia; Department of Surgery, Mongi Slim Hospital La Marsa, Tunisia.

出版信息

Int J Surg Case Rep. 2024 Oct;123:110266. doi: 10.1016/j.ijscr.2024.110266. Epub 2024 Sep 10.

Abstract

INTRODUCTION AND IMPORTANCE

Schistosomal appendicitis is a rare disease, with reported prevalence rates ranging from 1.31 to 3.2 %. The presented case underscores the critical significance of considering appendicular schistosomiasis as a potential etiology in cases of acute appendicitis, emphasizing the necessity of comprehensive histopathological examination for accurate diagnosis and appropriate postoperative management.

CASE PRESENTATION

A 29-year-old man from Guinea, with no significant medical history, presented with vomiting, persistent abdominal pain, and fatigue over five days. Physical examination revealed signs of peritoneal irritation and imaging showed features indicative of acute appendicitis. An appendectomy was conducted laparoscopically. Histological examination confirmed gangrenous appendicitis with the presence of schistosome eggs, diagnosing acute gangrenous appendicitis with schistosomiasis. The patient recovered well postoperatively and was discharged after treatment with praziquantel.

CLINICAL DISCUSSION

The clinical presentation of schistosomal appendicitis resembles that of other acute appendicitis cases. When suspicion arises due to risk factors, confirming schistosomiasis may involve serology, polymerase chain reaction assays, and identifying eggs in urine or feces. Computed tomography findings cannot distinguish acute appendicitis caused by Schistosoma species from other causes.

CONCLUSIONS

Histopathological appendix analysis is crucial for detecting conditions like schistosomiasis, warranting postoperative care. Praziquantel therapy post-surgery is vital for eradicating the disease and preventing complications.

摘要

引言与重要性

血吸虫性阑尾炎是一种罕见疾病,报告的患病率在1.31%至3.2%之间。本病例强调了在急性阑尾炎病例中,将阑尾血吸虫病视为潜在病因的关键意义,凸显了进行全面组织病理学检查以准确诊断和进行适当术后管理的必要性。

病例介绍

一名来自几内亚的29岁男子,无重大病史,出现呕吐、持续性腹痛和疲劳达五天。体格检查发现有腹膜刺激征,影像学检查显示有急性阑尾炎的特征。通过腹腔镜进行了阑尾切除术。组织学检查证实为坏疽性阑尾炎并存在血吸虫卵,诊断为急性坏疽性阑尾炎合并血吸虫病。患者术后恢复良好,经吡喹酮治疗后出院。

临床讨论

血吸虫性阑尾炎的临床表现与其他急性阑尾炎病例相似。当因危险因素产生怀疑时,确诊血吸虫病可能需要进行血清学检查、聚合酶链反应检测以及在尿液或粪便中发现虫卵。计算机断层扫描结果无法区分由血吸虫引起的急性阑尾炎与其他病因导致的急性阑尾炎。

结论

阑尾组织病理学分析对于检测血吸虫病等病症至关重要,术后护理也很有必要。术后使用吡喹酮治疗对于根除疾病和预防并发症至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a25/11415877/65beb07e3dfe/gr1.jpg

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