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[血吸虫病的阑尾定位:即时组织学检查的价值]

[Appendiceal localization of bilharziasis: value of extemporaneous histological examination].

作者信息

Panis Y, Kaisserian G, Sulahian A, Hoang C, Gallian A, Valleur P

机构信息

Service de Chirurgie digestive, Hôpital Lariboisière, Paris.

出版信息

Ann Chir. 1994;48(4):374-6.

PMID:8085764
Abstract

The association of appendicitis with schistosomiasis in the appendix is extremely rare in France. We report herein a new case in which the diagnosis was made, in the presence of pseudo-tumoral appendicitis, by frozen section biopsies. The patient presented with a typical acute appendicitis, without urinary symptoms, and with granulocytosis (14000 white cells/mm3, without eosinophilia). At laparotomy, the appendix was voluminous, with necrotic abscess, and lymph node masses were noted on the greater omentum. Frozen section biopsies of an omental tumor showed schistosoma eggs, without malignant cells. Appendicectomy and partial omentectomy were performed. Postoperative course was uneventful. Pathologic examination of the resected specimen showed schistosoma eggs in all layers of the appendix, and in the omentum. Final diagnosis was established by positive serology and by findings Schistosoma haematobium eggs in the urine. The patient was treated postoperatively by praziquantel. In conclusion, in case of acute appendicitis, with pseudotumorous appendix and lymph node masses, even with poor epidemiological findings on the clinical history, frozen section biopsies can sometimes establish the diagnosis of schistosomiasis with appendicitis, and avoid unjustified bowel resection.

摘要

在法国,阑尾炎与阑尾血吸虫病的关联极为罕见。我们在此报告一例新病例,该病例在出现假肿瘤性阑尾炎时,通过冰冻切片活检做出了诊断。患者表现为典型的急性阑尾炎,无泌尿系统症状,伴有粒细胞增多(白细胞计数为14000/mm³,无嗜酸性粒细胞增多)。剖腹手术时,阑尾肿大,有坏死性脓肿,大网膜上可见淋巴结肿块。对网膜肿瘤进行冰冻切片活检显示有血吸虫卵,无恶性细胞。实施了阑尾切除术和部分网膜切除术。术后病程顺利。切除标本的病理检查显示阑尾各层及网膜中均有血吸虫卵。最终诊断通过血清学阳性以及尿液中发现埃及血吸虫卵得以确立。患者术后接受了吡喹酮治疗。总之,对于急性阑尾炎伴有假肿瘤性阑尾和淋巴结肿块的情况,即使临床病史中的流行病学调查结果不佳,冰冻切片活检有时也能确立血吸虫病合并阑尾炎的诊断,避免不必要的肠道切除术。

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