Zhang Yahui, Cui Haowen, Xia Haian
Jiangsu Co-Innovation Center for Efficient Processing andUtilization of Forest Resources, College of Chemical Engineering, Nanjing Forestry University, Nanjing, Jiangsu, 210037, China.
ChemSusChem. 2025 Feb 1;18(3):e202401390. doi: 10.1002/cssc.202401390. Epub 2024 Oct 30.
2,5-furandicarboxylic acid (FDCA) is an important organic platform compound that has been widely used in the fields of medicine, pesticides, dyes, plastics and resins due to its unique structure and properties. In recent years, with the emphasis on sustainable development and green chemistry, the synthesis of FDCA from biomass has attracted extensive attention. The catalytic conversion of furfural (FF) to FDCA has the advantages of easy availability of the raw material, environmental friendliness, economic feasibility and so on, which is an important direction for FDCA synthesis in the future. This paper mainly reviews the prepare pathways of furoic acid (FA) and FDCA using FF as a starting material, including the selective conversion of FF and FA to target products under different types of catalysts. First, the research progress in the synthesis of FA from FF was summarized, and then the advances in the catalytic conversion of FA to FDCA was reviewed. In addition, the development of efficient and green catalysts and the optimization of existing synthesis protocols are emphasized as key factors to improve the yield and purity of FDCA while reducing production costs. Finally, the opportunities and challenges were discussed.
2,5-呋喃二甲酸（FDCA）是一种重要的有机平台化合物，因其独特的结构和性质，已在医药、农药、染料、塑料和树脂等领域得到广泛应用。近年来，随着对可持续发展和绿色化学的重视，由生物质合成FDCA引起了广泛关注。糠醛（FF）催化转化为FDCA具有原料易得、环境友好、经济可行等优点，是未来FDCA合成的一个重要方向。本文主要综述了以FF为原料制备糠酸（FA）和FDCA的途径，包括在不同类型催化剂作用下FF和FA向目标产物的选择性转化。首先，总结了由FF合成FA的研究进展，然后综述了FA催化转化为FDCA的研究进展。此外，强调开发高效绿色催化剂和优化现有合成方案是提高FDCA产率和纯度同时降低生产成本的关键因素。最后，讨论了机遇和挑战。
