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高身体质量指数与全球缺血性心脏病所致死亡和伤残调整生命年变化趋势,1990-2019 年。

Trends in deaths and disability-adjusted life-years of ischemic heart disease attributable to high body-mass index worldwide, 1990-2019.

机构信息

Department of cardiovascular internal medicine, Yuyao People's Hospital, 800 Chengdong Road, Yuyao, 315400, Zhejiang, China.

出版信息

BMC Cardiovasc Disord. 2024 Sep 11;24(1):482. doi: 10.1186/s12872-024-04136-y.

Abstract

BACKGROUND

The objective of this study is to evaluate the global burden of ischemic heart disease (IHD) attributable to High body mass index (HBMI) by utilizing data from Global Burden of Disease (GBD) 2019.

METHODS

This study utilized data from the GBD 2019 to examine the impact of HBMI on deaths and disability-adjusted life years (DALYs). The analysis focused on age-standardized rates and considered a 30-year time frame. Trends were assessed using estimated annual percentage changes (EAPCs).

RESULTS

Since 1990, a significant global increase in IHD attributable to HBMI has been observed. This increase is particularly notable among elderly males and in regions with low-middle Socio-Demographic Index (SDI), such as Central Asia and Eastern Europe. In 2019, IHD globally resulted in 1,662,339 deaths and 41,369,773 DALYs. Despite the high age-standardized death rate (20.73 per 100,000) and DALY rate (499.41 per 100,000), a declining trend was noted. This trend is reflected by the EAPCs of -0.35 for DALYs and - 0.67 for deaths. Notably, males and middle SDI countries exhibited higher rates of IHD, whereas high SDI regions such as High-income Asia Pacific and Western Europe showed decreasing trends in IHD.

CONCLUSION

Over the past three decades, there has been a significant increase in IHD caused by HBMI, especially in low-middle and low SDI regions. This highlights the importance of targeted interventions in addressing this issue. Notably, regions including Central Asia, Eastern Europe, North Africa, and the Middle East have been heavily affected.

摘要

背景

本研究旨在利用 2019 年全球疾病负担(GBD)的数据评估高身体质量指数(HBMI)导致的缺血性心脏病(IHD)的全球负担。

方法

本研究利用 GBD 2019 的数据,考察 HBMI 对死亡和伤残调整生命年(DALYs)的影响。分析侧重于年龄标准化率,并考虑了 30 年的时间范围。使用估计的年度百分比变化(EAPC)评估趋势。

结果

自 1990 年以来,HBMI 导致的 IHD 全球负担显著增加。这种增加在老年男性和中低社会发展指数(SDI)地区尤为明显,如中亚和东欧。2019 年,全球 IHD 导致 1662339 人死亡和 41369773 人伤残调整生命年。尽管年龄标准化死亡率(20.73/10 万)和 DALY 率(499.41/10 万)较高,但呈下降趋势。这一趋势反映在 DALY 的 EAPC 为-0.35 和死亡的 EAPC 为-0.67。值得注意的是,男性和中 SDI 国家的 IHD 发病率较高,而高 SDI 地区,如亚太高收入地区和西欧,IHD 呈下降趋势。

结论

在过去三十年中,HBMI 导致的 IHD 显著增加,特别是在中低和低 SDI 地区。这凸显了针对这一问题采取针对性干预措施的重要性。值得注意的是,包括中亚、东欧、北非和中东在内的地区受到了严重影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cee1/11389382/2c8e71579523/12872_2024_4136_Fig1_HTML.jpg

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