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1990 年至 2019 年期间,因膳食纤维摄入不足导致的缺血性心脏病全球负担分析。

A global analysis of the burden of ischemic heart disease attributable to diet low in fiber between 1990 and 2019.

机构信息

Department of General Medicine, The first affiliated hospital of Bengbu Medical University, Bengbu, 233004, Anhui, China.

Department of Cardiovascular Medicine, The first affiliated hospital of Bengbu Medical University, Bengbu, China.

出版信息

BMC Cardiovasc Disord. 2024 Sep 14;24(1):491. doi: 10.1186/s12872-024-04156-8.

Abstract

AIM

Ischemic heart disease (IHD) represents a major cardiovascular condition heavily influenced by dietary factors. This study endeavors to assess the global, regional, and temporal impact of low-fiber diets on the burden of IHD.

METHOD

Leveraging data from the Global Burden of Disease (GBD) 2019 study, we analyzed the worldwide burden of IHD resulting from diet low in fiber using indices including death and disability-adjusted life years (DALY). This burden was further segmented based on variables including regions and countries. To track the evolution from 1990 to 2019, we utilized the Joinpoint regression model to estimate the temporal trend of IHD burden stemming from low-fiber diets.

RESULTS

In 2019, a total of 348.85 thousand (95%UI: 147.57, 568.31) deaths and 7942.96 thousand (95%UI: 3373.58,12978.29) DALY (95% UI: 707.88, 1818) of IHD were attributed to diet low in fiber globally. These figures correspond to 3.82% of all IHD deaths and 4.36% of total IHD DALYs. The age-standardized death and DALY rates per 100,000 individuals were 4.48 (95% UI: 1.90,7.27) and 97.4(95%UI: 41.44, 158.88) respectively. However, significant regional disparities emerged in these age-standardized rates, with South Asia and Central Asia experiencing the highest rates. Between 1990 and 2019, we observed that most regions displayed a downward trend of the age-standardized DALY and death rate of IHD resulting from low-fiber diets, except for Central Sub-Saharan Africa and Southern Sub-Saharan Africa.

CONCLUSION

Our analysis underscores the substantial toll of IHD associated with low-fiber diets, particularly considering the significant regional variations. Therefore, it is imperative to sustain efforts to implement effective measures aimed at enhancing fiber intake worldwide, particularly in countries with lower socio-demographic indices.

摘要

目的

缺血性心脏病(IHD)是一种主要的心血管疾病,其发病受到饮食因素的极大影响。本研究旨在评估低纤维饮食对 IHD 疾病负担的全球、区域和时间变化的影响。

方法

利用 2019 年全球疾病负担研究(GBD)的数据,我们分析了因低纤维饮食导致的 IHD 的死亡人数和伤残调整生命年(DALY)的全球负担。还根据区域和国家等变量对这一负担进行了细分。为了跟踪 1990 年至 2019 年的演变情况,我们使用 Joinpoint 回归模型来估计低纤维饮食导致的 IHD 负担的时间趋势。

结果

2019 年,全球共有 34.885 万人(95%UI:14.757,56.831)死于 IHD,全球因低纤维饮食导致的 IHD 伤残调整生命年(DALY)为 7942.96 万人(95%UI:3373.58,12978.29)。这相当于所有 IHD 死亡人数的 3.82%和 IHD 总 DALY 的 4.36%。每 10 万人标准化后的死亡率和 DALY 率分别为 44.8(95%UI:19.0,72.7)和 974(95%UI:41.44,158.88)。然而,这些标准化后的比率在区域间存在显著差异,南亚和中亚的比率最高。1990 年至 2019 年期间,我们发现除了中撒哈拉非洲和南撒哈拉非洲之外,大多数地区因低纤维饮食导致的 IHD 标准化 DALY 和死亡率呈下降趋势。

结论

我们的分析强调了与低纤维饮食相关的 IHD 所带来的巨大负担,特别是考虑到其在区域间的显著差异。因此,有必要继续努力在全球范围内实施有效的措施,以增加纤维摄入量,特别是在社会人口指数较低的国家。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3231/11401411/961862cfddfa/12872_2024_4156_Fig1_HTML.jpg

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