Department of Neurosurgery, The Aga Khan University, Karachi, Pakistan.
CyberKnife and Tomotherapy Centre, Jinnah Post Graduate Medical Centre, Karachi, Pakistan.
J Pak Med Assoc. 2024 Mar;74(3 (Supple-3)):S152-S158. doi: 10.47391/JPMA.S3.GNO-18.
Intra-cranial meningiomas represent the most common type of extra-axial brain tumour in adults. Characteristically slow-growing and often asymptomatic, these tumours may only require observation in some cases. However, lesions that cause a significant mass effect necessitate intervention, primarily through surgical means. Additionally, in cases of significant unresectable low-grade residual meningioma or high-grade tumours, radiation therapy becomes essential. Notably, current management guidelines predominantly reflect data derived from high-income countries, failing to address constraints prevalent in the developing world, such as limited financial resources and restricted access to advanced surgical facilities. This manuscript introduces guidelines specifically tailored for the management of meningioma in patients from low- and middle-income countries, considering their unique healthcare challenges and resources.
颅内脑膜瘤是成年人最常见的颅内肿瘤。这些肿瘤生长缓慢，通常无症状，在某些情况下仅需要观察。然而，引起明显占位效应的病变需要干预，主要通过手术方式。此外，对于明显无法切除的低级别残留脑膜瘤或高级别肿瘤，放射治疗至关重要。值得注意的是，目前的管理指南主要反映了来自高收入国家的数据，未能解决发展中国家普遍存在的限制因素，如有限的财政资源和获得先进手术设施的机会有限。本文介绍了专门针对中低收入国家患者脑膜瘤管理的指南，考虑了他们独特的医疗保健挑战和资源。
