Icahn School of Medicine at Mount Sinai, New York, NY, USA.
University Hospital Münster, Münster, Germany.
Acta Derm Venereol. 2024 Sep 11;104:adv39941. doi: 10.2340/actadv.v104.39941.
Notalgia paresthetica (NP) is a sensory neuropathy characterized by chronic pruritus, skin pain, and other pathologic sensations affecting the mid-to-upper back. NP may be under-recognized and under-diagnosed, with limited data available on its symptom presentation and treatment patterns. NP-DERM was an internet-based survey of dermatologists (n = 650) from 8 different countries on their perspectives on NP symptoms and current treatment practices. Dermatologists typically treated a median of 12 patients with NP per month. Dermatologists reported that itch (pruritus) was the most common symptom for their patients with NP, followed by hyperpigmentation and sensitive skin. The most burdensome NP symptom was pruritus, followed by burning or hot sensation, and painful or raw skin. The most prescribed treatments included non-medicated skin care, topical corticosteroids, oral antihistamines, medicated topicals, and gabapentin or pregabalin. Physicians reported low satisfaction with available treatments. The most common reason for physicians to discontinue patients' therapy was lack of response.
感觉异常性背疼(NP)是一种感觉神经病变,其特征为慢性瘙痒、皮肤疼痛和其他影响中上背部的病理性感觉。NP 可能未被充分认识和诊断,其症状表现和治疗模式的数据有限。NP-DERM 是一项针对 8 个不同国家的皮肤科医生(n=650)的在线调查,了解他们对 NP 症状和当前治疗实践的看法。皮肤科医生通常每月治疗 12 名 NP 患者。皮肤科医生报告说,他们的 NP 患者最常见的症状是瘙痒(瘙痒),其次是色素沉着和敏感皮肤。最困扰 NP 的症状是瘙痒,其次是烧灼感或热感,以及疼痛或皮肤破损。最常开的治疗方法包括非药物性皮肤护理、局部皮质类固醇、口服抗组胺药、药物性局部制剂和加巴喷丁或普瑞巴林。医生报告说,对现有治疗方法的满意度较低。医生停止患者治疗的最常见原因是缺乏反应。