Li Bangyang, Cai Peng, Zhao Xue, Li Weijuan, Yang Juan, Xia Xuefei, Ma Lei
School of Nursing, Guizhou Medical University Guiyang 550000, Guizhou, China.
Nursing Department, The Affiliated Hospital of Guizhou Medical University Guiyang 550000, Guizhou, China.
Am J Transl Res. 2024 Aug 15;16(8):3498-3509. doi: 10.62347/SRIC1173. eCollection 2024.
Patients with hemodialysis (HD) frequently encounter stigma, which impacts their social network and adherence to treatment, increasing their risk of depression and lowering their quality of life. The factors associated with stigma among patients with HD remain poorly understood due to insufficient evidence. To fill this gap, this meta-analysis was conducted.
We carried out a thorough literature review in both Chinese and English databases like China National Knowledge Infrastructure (CNKI), Wan Fang Knowledge Data Service Platform, PubMed, Embase, PsycINFO, CINAHL (Cumulative Index to Nursing and Allied Health Literature) and Web of Science. We included literature up to May 25, 2024, focusing on the levels and factors related to stigma in HD patients. Data extraction and quality assessment of the included literature were separately carried out by two researchers, who also independently did the literature screening. Data analysis was carried out using Stata 15.1 software. The possible sources of heterogeneity were explored by sensitivity analysis and subgroup analysis, and the robustness of the results was evaluated.
A total of 12 papers were included, and the quality of these papers was evaluated as moderate or above. The findings of the meta-analysis demonstrated that the pooled stigma mean score was 59.30 [95% (Confidence interval) : 55.62 to 62.97]. Per capita monthly family income [ =4.95, 95% CI (1.55 to 8.35), =0.004], residence [=-4.66, 95% CI (-6.96 to -2.36), <0.001], complications [=4.76, 95% CI (0.92 to 8.61), =0.015], family function [=-0.29, 95% CI (-0.38 to -0.21), <0.001], self-efficacy [=-0.37, 95% CI (-0.48 to -0.26), <0.001], levels of social support [=-0.35, 95% CI (-0.45 to -0.25), <0.001], and levels of psychological distress [=0.59, 95% CI (0.26 to 0.91), <0.001] were all significant factors contributing to stigma in patients undergoing HD.
Healthcare professionals should pay attention to the early assessment of stigma in patients with HD, implement personalized interventions targeting related factors, and promote effective coping strategies for managing the disease.
血液透析（HD）患者经常遭遇污名化，这影响了他们的社交网络和对治疗的依从性，增加了他们患抑郁症的风险并降低了生活质量。由于证据不足，HD患者中与污名化相关的因素仍知之甚少。为填补这一空白，进行了这项荟萃分析。
我们在中国知网（CNKI）、万方知识数据服务平台、PubMed、Embase、PsycINFO、护理学与健康相关文献累积索引（CINAHL）和Web of Science等中英文数据库中进行了全面的文献综述。我们纳入了截至2024年5月25日的文献，重点关注HD患者污名化的程度和相关因素。两名研究人员分别对纳入文献进行数据提取和质量评估，他们也独立进行文献筛选。使用Stata 15.1软件进行数据分析。通过敏感性分析和亚组分析探索异质性的可能来源，并评估结果的稳健性。
共纳入12篇论文，这些论文的质量评估为中等及以上。荟萃分析结果表明，合并后的污名化平均评分为59.30 [95%（置信区间）：55.62至62.97]。人均家庭月收入[β = 4.95，95% CI（1.55至8.35），P = 0.004]、居住地区[β = -4.66，95% CI（-6.96至-2.36），P < 0.001]、并发症[β = 4.76，95% CI（0.92至8.61），P = 0.015]、家庭功能[β = -0.29，95% CI（-0.38至-0.21），P < 0.001]、自我效能感[β = -0.37，95% CI（-0.48至-0.
