颅内压增高——会有一种病毒正在引发吗？
ICP - could there be a virus in the works?
作者信息
Giles Sarah K, Hague Wm Bill, Edwards Robert A
机构信息
Flinders Accelerator for Microbiome Exploration, Flinders University, Bedford Park, SA, Australia.
Robinson Research Institute, The University of Adelaide, North Adelaide, SA, Australia.
出版信息
Obstet Med. 2024 Sep;17(3):175-178. doi: 10.1177/1753495X241258385. Epub 2024 Jun 6.
Intrahepatic cholestasis of pregnancy (ICP) is the most common liver-specific disorder affecting pregnant women, with an Australian incidence of 0.6% pa and recurring in 70% of those affected. ICP causes mild to severe pruritus, often resulting in considerable skin excoriations, profound sleep disturbances, and severe anxiety, and yet the aetiology and optimal treatment or management of this condition remains unknown. In this review, we consider the role of viruses in causing or exacerbating ICP and discuss viruses that have been most closely implicated in the disease, including the role of Hepatitis B and Hepatitis C viruses in ICP.
妊娠肝内胆汁淤积症（ICP）是影响孕妇的最常见的肝脏特异性疾病，在澳大利亚的发病率为每年0.6%，70%的患者会复发。ICP会导致轻度至重度瘙痒，常导致严重的皮肤擦伤、深度睡眠障碍和严重焦虑，然而这种疾病的病因以及最佳治疗或管理方法仍然未知。在这篇综述中，我们探讨病毒在引发或加重ICP方面的作用，并讨论与该疾病关系最为密切的病毒，包括乙型肝炎病毒和丙型肝炎病毒在ICP中的作用。
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