Dairo Kolapo, Bishop Ryan, Sethia Rishabh, Old Matthew, Jatana Kris R, Elmaraghy Charles A
College of Medicine, The Ohio State University, Columbus, OH, USA.
Department of Otolaryngology, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
Transl Pediatr. 2024 Aug 31;13(8):1503-1509. doi: 10.21037/tp-24-4. Epub 2024 Aug 27.
Microvascular free-tissue transfer is a widely used technique for surgical site reconstruction following head and neck mass resection. While it is commonly used in adults, the rarity of head and neck cancers in children makes free flap reconstruction relatively rare in this population. Free flap reconstruction allows for coverage of large defects which may result from wide resections performed to avoid exposing pediatric patients to primary radiotherapy.
We present two pediatric oncologic cases using free flap reconstruction. The first, a 4-year-old male, presented with a rapidly enlarging tongue lesion that was diagnosed as a biphasic synovial sarcoma. The mass was resected, and a radial forearm free flap was placed. The second, a 9-year-old male, presented with jaw pain and a mandibular mass. Biopsy confirmed a diagnosis of Ewing sarcoma. The patient was treated initially with chemotherapy, followed by surgical resection and placement of an osteocutaneous fibular free flap. Both patients are disease-free 5 years post-operation.
In each patient, complete resection of the primary tumor was performed eliminating the need for radiotherapy with utilization of free flap reconstruction. As advances in medicine enable better evaluation of clear margins resulting in larger resection defects, free tissue transfer provides a useful reconstructive option in the pediatric population.
微血管游离组织移植是头颈部肿物切除术后手术部位重建广泛应用的技术。虽然它在成人中常用,但儿童头颈部癌症罕见,使得游离皮瓣重建在该人群中相对少见。游离皮瓣重建可用于覆盖因广泛切除以避免儿科患者接受原发放疗而可能导致的大缺损。
我们展示两例采用游离皮瓣重建的儿科肿瘤病例。第一例,一名4岁男性,出现迅速增大的舌部肿物,诊断为双相滑膜肉瘤。肿物切除后,置入桡侧前臂游离皮瓣。第二例,一名9岁男性,出现颌部疼痛和下颌肿物。活检确诊为尤因肉瘤。患者最初接受化疗,随后进行手术切除并置入腓骨骨皮游离皮瓣。两名患者术后5年均无疾病。
在每例患者中,均进行了原发肿瘤的完整切除,通过游离皮瓣重建无需放疗。随着医学进步能够更好地评估切缘阴性从而导致更大的切除缺损,游离组织移植为儿科人群提供了一种有用的重建选择。