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人参对更年期的潜在益处。

The beneficial potential of ginseng for menopause.

作者信息

Song JiHyeon, Lee Namkyu, Yang Hyun-Jeong, Lee Myeong Soo, Kopalli Spandana Rajendra, Kim Yong-Ung, Lee YoungJoo

机构信息

Department of Integrative Bioscience and Biotechnology, College of Life Science, Sejong University, Seoul, Republic of Korea.

Department of Integrative Healthcare, University of Brain Education, Cheonan, Republic of Korea.

出版信息

J Ginseng Res. 2024 Sep;48(5):449-453. doi: 10.1016/j.jgr.2024.05.008. Epub 2024 May 31.

DOI:10.1016/j.jgr.2024.05.008
PMID:39263310
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11385173/
Abstract

Korean Red Ginseng (KRG) has long been used not only as a food supplement but also as a treatment for various diseases. Ginseng originated in South Korea, which later spread to China and Japan, has a wide range of pharmacological activities including immune, endocrine, cardiovascular, and central nervous system effects. KRG is produced by repetitions of steaming and drying of ginseng to extend preservation. During this steaming process, the components of ginseng undergo physio-chemical changes forming a variety of potential active constituents including ginsenoside-Rg3, a unique compound in KRG. Pandemic Coronavirus disease 2019 (COVID-19), has affected both men and women differentially. In particular, women were more vulnerable to COVID-related distress which in turn could aggravate menopause-related disturbances. Complementary and alternative medicinal plants could have aided middle-aged women for several menopause-related symptoms during and post COVID-19 pandemic. This review aimed to explore the beneficial effects of KRG on menopausal symptoms and gynecological cancer.

摘要

韩国红参(KRG)长期以来不仅被用作食品补充剂,还被用于治疗各种疾病。人参原产于韩国,后来传播到中国和日本,具有广泛的药理活性,包括对免疫、内分泌、心血管和中枢神经系统的作用。韩国红参是通过对人参反复进行蒸制和干燥以延长保存期而制成的。在这个蒸制过程中,人参的成分会发生物理化学变化,形成多种潜在的活性成分,包括人参皂苷-Rg3,这是韩国红参中的一种独特化合物。2019年大流行性冠状病毒病(COVID-19)对男性和女性的影响存在差异。特别是,女性更容易受到与COVID相关的困扰,而这反过来又可能加剧与更年期相关的紊乱。在COVID-19大流行期间及之后,补充和替代药用植物可能有助于中年女性缓解一些与更年期相关的症状。本综述旨在探讨韩国红参对更年期症状和妇科癌症的有益作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d5a7/11385173/3237e15c602a/ga1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d5a7/11385173/3237e15c602a/ga1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d5a7/11385173/3237e15c602a/ga1.jpg

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本文引用的文献

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KRG and its major ginsenosides do not show distinct steroidogenic activities examined by the OECD test guideline 440 and 456 assays.根据经合组织测试指南440和456分析,红参及其主要人参皂苷未显示出明显的类固醇生成活性。
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Effects of Panax Ginseng on Health-Related Quality of Life in Patients with Non-Metastatic Breast Cancer: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial Ginseng for HRQOL in Breast Cancer.人参对非转移性乳腺癌患者健康相关生活质量的影响:一项随机、双盲、安慰剂对照的临床试验 人参对乳腺癌患者 HRQOL 的影响。
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根据载脂蛋白E4等位基因状态,老年人服用人参与阿尔茨海默病特异性认知的关系。
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C.A. meyer alleviates benign prostatic hyperplasia while preventing finasteride-induced side effects.C.A. 迈耶在预防非那雄胺引起的副作用的同时减轻良性前列腺增生。
Front Pharmacol. 2023 Jan 12;14:1039622. doi: 10.3389/fphar.2023.1039622. eCollection 2023.
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Cytotoxic Properties of C Polyacetylenes from the Fresh Roots of on Human Epithelial Ovarian Cancer Cells.从新鲜的 根中提取的 C 聚乙炔对人上皮性卵巢癌细胞的细胞毒性作用。
Molecules. 2022 Oct 18;27(20):7027. doi: 10.3390/molecules27207027.
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J Oncol Pharm Pract. 2023 Sep;29(6):1306-1316. doi: 10.1177/10781552221118530. Epub 2022 Aug 17.
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Protective role of ginseng in endometriosis during covid-19.人参在新冠疫情期间对子宫内膜异位症的保护作用。
J Ginseng Res. 2023 Mar;47(2):169-172. doi: 10.1016/j.jgr.2022.08.002. Epub 2022 Aug 11.
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