从莫哈韦响尾蛇（Crotalus scutulatus scutulatus）毒液中分离出两种磷脂酶A2以及不同种群中免疫相关毒液蛋白的变异情况。
Isolation of two phospholipases A2 from Mojave rattlesnake (Crotalus scutulatus scutulatus) venom and variation of immunologically related venom proteins in different populations.
作者信息
Zepeda H, Rael E D, Knight R A
出版信息
Comp Biochem Physiol B. 1985;81(2):319-24. doi: 10.1016/0305-0491(85)90320-7.
Two phospholipases A2 of mol. wt 14,500 (P1) and 14,400 (P2) and pI 9.2 and 7.4 respectively were isolated from Crotalus scutulatus scutulatus venom. The two isoenzymes cross-reacted immunologically with phospholipase A2 from C. adamanteus and C, atrox, but not with Mojave toxin, excluding them as the basic subunit of the Mojave toxin complex. C. s. scutulatus venoms from Arizona had two common bands recognized by anti-P2 which were absent in most C. s. scutulatus venoms from Texas, suggesting two genetically different populations east and west of the Continental Divide.
从角响尾蛇（Crotalus scutulatus scutulatus）毒液中分离出两种分子量分别为14,500（P1）和14,400（P2）、等电点分别为9.2和7.4的磷脂酶A2。这两种同工酶与矛头蝮（C. adamanteus）和草原响尾蛇（C. atrox）的磷脂酶A2发生免疫交叉反应，但与莫哈韦毒素不发生反应，因此排除它们是莫哈韦毒素复合物的基本亚基。来自亚利桑那州的角响尾蛇毒液有两条能被抗P2识别的共同条带，而大多数来自得克萨斯州的角响尾蛇毒液中没有这两条带，这表明在大陆分水岭东西两侧存在两个基因不同的种群。
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