比较炎症标志物在预测冷冻消融术后心房颤动复发中的作用。
Comparison of inflammatory markers for the prediction of atrial fibrillation recurrence following cryoablation.
机构信息
Department of Cardiology, Health Sciences University, Dr Siyami Ersek Cardiovascular & Thoracic Surgery Center, Istanbul, Turkey.
Department of Medicine, University of Maryland Midtown Campus, Baltimore, MD 21201, USA.
出版信息
Biomark Med. 2024;18(17-18):717-725. doi: 10.1080/17520363.2024.2395236. Epub 2024 Sep 12.
Abstract
The aim of this study is to investigate the value of inflammatory markers for atrial fibrillation (AF) recurrence prediction after cryo-balloon ablation (CA). The study included 399 patients divided into two groups by AF recurrence after CA. Inflammatory markers including uric acid/albumin ratio (UAR), systemic immune inflammation index (SIII) and CRP/albumin ratio (CAR) were evaluated. UAR, SIII, and CAR were independently associated with the risk of recurrence in AF patients following CA. In ROC curve analysis, CAR had a greater area under curve (AUC:0.73) value than either SIII (AUC:0.68) or UAR (AUC:0.64). Our study results indicate that CAR compared with SIII and UAR had a greater predictive value than others inflammatory markers in predicting AF recurrence post-CA.
摘要
本研究旨在探讨炎症标志物在冷冻球囊消融（CA）后预测心房颤动（AF）复发中的价值。该研究纳入了 399 名患者，根据 CA 后 AF 复发情况分为两组。评估了包括尿酸/白蛋白比值（UAR）、全身免疫炎症指数（SIII）和 CRP/白蛋白比值（CAR）在内的炎症标志物。UAR、SIII 和 CAR 均与 CA 后 AF 患者的复发风险独立相关。在 ROC 曲线分析中，CAR 的曲线下面积（AUC：0.73）值大于 SIII（AUC：0.68）或 UAR（AUC：0.64）。我们的研究结果表明，与 SIII 和 UAR 相比，CAR 在预测 CA 后 AF 复发方面具有比其他炎症标志物更高的预测价值。
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