Mehta Shanti, Metko Dea, Lam Joseph M
Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
Michael G. DeGroote School of Medicine, McMaster University, Hamilton, Ontario, Canada.
Pediatr Dermatol. 2025 Jan-Feb;42(1):91-94. doi: 10.1111/pde.15746. Epub 2024 Sep 12.
The relationship between HS and obesity, while well established in adult patients, has drawn increased attention in pediatric patients given the rising prevalence of pediatric obesity worldwide. This review aims to consolidate existing evidence of the relationship between HS and obesity in the pediatric population and to hypothesize about reasons for an association between the two conditions. Our cohort comprised 2911 patients with a mean age of 11.4 years at the age of onset of HS, and based on body mass index (BMI), 42.3% of patients were classified as obese (BMI > 30), and 14% were overweight (BMI 25-29.9). Our findings indicate an association between obesity and HS in pediatric patients, which may be explained through numerous mechanisms, including shared genetic factors, hereditary relationships, and the impact of HS on adolescents' quality of life.
虽然化脓性汗腺炎（HS）与肥胖之间的关系在成年患者中已得到充分证实，但鉴于全球儿童肥胖患病率不断上升，这一关系在儿科患者中也越来越受到关注。本综述旨在整合儿科人群中HS与肥胖之间关系的现有证据，并推测这两种情况之间存在关联的原因。我们的队列包括2911例HS发病时平均年龄为11.4岁的患者，根据体重指数（BMI），42.3%的患者被归类为肥胖（BMI>30），14%为超重（BMI 25-29.9）。我们的研究结果表明，儿科患者中肥胖与HS之间存在关联，这可能通过多种机制来解释，包括共同的遗传因素、遗传关系以及HS对青少年生活质量的影响。
