• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

儿童化脓性汗腺炎的临床特征:一项横断面多中心研究,共纳入 140 例患者。

Clinical characteristics of pediatric hidradenitis suppurativa: a cross-sectional multicenter study of 140 patients.

机构信息

Department of Dermatology, Zealand University Hospital, Sygehusvej 5, 4000, Roskilde, Denmark.

Health Sciences Faculty, University of Copenhagen, Copenhagen, Denmark.

出版信息

Arch Dermatol Res. 2020 Dec;312(10):715-724. doi: 10.1007/s00403-020-02053-6. Epub 2020 Mar 12.

DOI:
10.1007/s00403-020-02053-6
PMID:32166376
Abstract

Hidradenitis suppurativa (HS) rarely affects pediatric patients. The literature on pediatric HS patients is scarce. This is a cross-sectional study based on case note review or interviews and clinical examination of 140 pediatric patients undergoing secondary or tertiary level care. Patients were predominantly female (75.5%, n = 105) with a median age of 16. 39% reported 1st-degree relative with HS. Median BMI percentile was 88, and 11% were smokers (n = 15). Median modified Sartorius score was 8.5. Notable comorbidities found were acne (32.8%, n = 45), hirsutism (19.3%, n = 27), and pilonidal cysts (16.4%, n = 23). Resorcinol (n = 27) and clindamycin (n = 25) were the most frequently used topical treatments. Patients were treated with tetracycline (n = 32), or oral clindamycin and rifampicin in combination (n = 29). Surgical excision was performed in 18 patients, deroofing in five and incision in seven patients. Obesity seemed to be prominent in the pediatric population and correlated to parent BMI, suggesting a potential for preventive measures for the family. Disease management appeared to be similar to that of adult HS, bearing in mind that the younger the patient, the milder the disease in majority of cases.

摘要

化脓性汗腺炎(HS)很少影响儿科患者。关于儿科 HS 患者的文献很少。这是一项基于病历回顾或访谈以及对 140 名接受二级或三级护理的儿科患者进行临床检查的横断面研究。患者主要为女性(75.5%,n=105),中位年龄为 16.39%的患者报告有一级亲属患有 HS。中位 BMI 百分位数为 88,11%的患者吸烟(n=15)。中位改良 Sartorius 评分 8.5。发现的显著合并症包括痤疮(32.8%,n=45)、多毛症(19.3%,n=27)和藏毛窦(16.4%,n=23)。间苯二酚(n=27)和克林霉素(n=25)是最常用的局部治疗药物。患者接受四环素(n=32)或口服克林霉素和利福平联合治疗(n=29)。18 名患者接受了手术切除,5 名患者接受了去顶术,7 名患者接受了切开术。肥胖在儿科人群中似乎很突出,与父母 BMI 相关,表明对家庭有预防措施的潜力。疾病管理似乎与成人 HS 相似,需要注意的是,大多数情况下,患者年龄越小,疾病越轻。

相似文献

1
Clinical characteristics of pediatric hidradenitis suppurativa: a cross-sectional multicenter study of 140 patients.儿童化脓性汗腺炎的临床特征:一项横断面多中心研究,共纳入 140 例患者。
Arch Dermatol Res. 2020 Dec;312(10):715-724. doi: 10.1007/s00403-020-02053-6. Epub 2020 Mar 12.
2
Pediatric Hidradenitis Suppurativa: A Cross-Sectional Study on Clinical Features and Treatment Approaches.儿童化脓性汗腺炎:临床特征和治疗方法的横断面研究。
J Cutan Med Surg. 2022 Mar-Apr;26(2):127-134. doi: 10.1177/12034754211039993. Epub 2021 Oct 6.
3
Oral clindamycin and rifampicin in the treatment of hidradenitis suppurativa-acne inversa: can some factors influence the response to the treatment?口服克林霉素和利福平治疗化脓性汗腺炎-反向性痤疮:某些因素会影响治疗反应吗?
G Ital Dermatol Venereol. 2016 Apr;151(2):216-8.
4
Baseline Characteristics from UNITE: An Observational, International, Multicentre Registry to Evaluate Hidradenitis Suppurativa (Acne Inversa) in Clinical Practice.UNITE 研究的基线特征:一项评估临床实践中化脓性汗腺炎(反向痤疮)的观察性、国际性、多中心登记研究。
Am J Clin Dermatol. 2020 Aug;21(4):579-590. doi: 10.1007/s40257-020-00504-4.
5
The efficacy and tolerability of tetracyclines and clindamycin plus rifampicin for the treatment of hidradenitis suppurativa: Results of a prospective European cohort study.四环素类药物和克林霉素联合利福平治疗化脓性汗腺炎的疗效和耐受性:一项前瞻性欧洲队列研究的结果。
J Am Acad Dermatol. 2021 Aug;85(2):369-378. doi: 10.1016/j.jaad.2020.12.089. Epub 2021 Jan 20.
6
Clindamycin versus clindamycin plus rifampicin in hidradenitis suppurativa treatment: Clinical and ultrasound observations.克林霉素与克林霉素加利福平治疗化脓性汗腺炎:临床和超声观察。
J Am Acad Dermatol. 2019 May;80(5):1314-1321. doi: 10.1016/j.jaad.2018.11.035. Epub 2018 Nov 28.
7
Diseases associated with hidranitis suppurativa: part 2 of a series on hidradenitis.与化脓性汗腺炎相关的疾病:汗腺炎系列文章的第2部分
Dermatol Online J. 2013 Jun 15;19(6):18558.
8
Pilonidal sinus disease: an intergluteal localization of hidradenitis suppurativa/acne inversa: a cross-sectional study among 2465 patients.藏毛窦疾病:化脓性汗腺炎/反向痤疮的臀间定位:2465 例患者的横断面研究。
Br J Dermatol. 2019 Dec;181(6):1198-1206. doi: 10.1111/bjd.17927. Epub 2019 May 6.
9
A Retrospective Cohort Study on Patients with Hidradenitis Suppurativa.一项关于化脓性汗腺炎患者的回顾性队列研究。
Dermatology. 2018;234(1-2):71-78. doi: 10.1159/000488344. Epub 2018 May 14.
10
Incidence of hidradenitis suppurativa and associated factors: a population-based study of Olmsted County, Minnesota.化脓性汗腺炎的发病率及相关因素:明尼苏达州奥姆斯特德县的一项基于人群的研究。
J Invest Dermatol. 2013 Jan;133(1):97-103. doi: 10.1038/jid.2012.255. Epub 2012 Aug 30.

引用本文的文献

1
Prevalence of Comorbidities Among Pediatric Patients With Hidradenitis Suppurativa: A Meta-Analysis.化脓性汗腺炎儿科患者合并症的患病率:一项荟萃分析。
JAMA Dermatol. 2025 Jun 11. doi: 10.1001/jamadermatol.2025.1565.
2
Ηidradenitis suppurativa associated with autoimmunity in children and adolescents; a case-based review.儿童和青少年中与自身免疫相关的化脓性汗腺炎;基于病例的综述。
Rheumatol Int. 2025 Mar 28;45(4):83. doi: 10.1007/s00296-025-05828-0.
3
Precocious Puberty Among Children and Adolescents With Hidradenitis Suppurativa.

本文引用的文献

1
Resident Memory and Recirculating Memory T Cells Cooperate to Maintain Disease in a Mouse Model of Vitiligo.驻留记忆和再循环记忆 T 细胞协同作用维持小鼠白癜风模型中的疾病。
J Invest Dermatol. 2019 Apr;139(4):769-778. doi: 10.1016/j.jid.2018.10.032. Epub 2018 Nov 10.
2
Hidradenitis suppurativa in children: The Henry Ford experience.儿童化脓性汗腺炎:亨利·福特医院的经验
Pediatr Dermatol. 2018 May;35(3):370-373. doi: 10.1111/pde.13466. Epub 2018 Mar 25.
3
Links between the organization of the family home environment and child obesity: a systematic review.
患有化脓性汗腺炎的儿童和青少年中的性早熟
JAMA Dermatol. 2024 Nov 1;160(11):1245-1246. doi: 10.1001/jamadermatol.2024.3104.
4
A Review of Hidradenitis Suppurativa in Special Populations: Considerations in Children, Pregnant and Breastfeeding Women, and the Elderly.特殊人群中的化脓性汗腺炎综述:儿童、孕妇和哺乳期妇女以及老年人的注意事项
Dermatol Ther (Heidelb). 2024 Sep;14(9):2407-2425. doi: 10.1007/s13555-024-01249-2. Epub 2024 Sep 4.
5
Hidradenitis Suppurativa in Children and Adolescents: An Update on Pharmacologic Treatment Options.儿童和青少年化脓性汗腺炎:药物治疗选择的最新进展。
Paediatr Drugs. 2023 Nov;25(6):659-676. doi: 10.1007/s40272-023-00595-6. Epub 2023 Oct 2.
6
Expert consensus on priority research gaps in dietary and lifestyle factors in hidradenitis suppurativa: a Delphi consensus study.专家共识:饮食和生活方式因素在化脓性汗腺炎中的优先研究空白:德尔菲共识研究。
Arch Dermatol Res. 2023 Sep;315(7):2129-2136. doi: 10.1007/s00403-023-02610-9. Epub 2023 Mar 23.
7
Biologic Use in Pediatric Patients With Hidradenitis Suppurativa: A Systematic Review.生物制剂在化脓性汗腺炎患儿中的应用:系统评价。
J Cutan Med Surg. 2022 Mar-Apr;26(2):176-180. doi: 10.1177/12034754211049711. Epub 2021 Sep 29.
8
Physical and psychosocial comorbidities of pediatric hidradenitis suppurativa: A retrospective analysis.儿童化脓性汗腺炎的躯体和心理共病:一项回顾性分析。
Pediatr Dermatol. 2021 Sep;38(5):1132-1136. doi: 10.1111/pde.14765. Epub 2021 Aug 31.
9
Pediatric hidradenitis suppurativa: epidemiology, disease presentation, and treatments.小儿化脓性汗腺炎:流行病学、疾病表现及治疗方法
J Dermatolog Treat. 2022 Jun;33(4):2391-2393. doi: 10.1080/09546634.2021.1937484. Epub 2022 Mar 23.
10
The most recent advances in understanding and managing hidradenitis suppurativa.化脓性汗腺炎的理解与管理方面的最新进展。
F1000Res. 2020 Aug 26;9. doi: 10.12688/f1000research.26083.1. eCollection 2020.
家庭居住环境组织与儿童肥胖之间的关系:系统评价。
Obes Rev. 2018 Mar 8;19(5):716-727. doi: 10.1111/obr.12662.
4
Somatic and psychiatric comorbidities of hidradenitis suppurativa in children and adolescents.儿童和青少年化脓性汗腺炎的躯体和精神共病。
J Am Acad Dermatol. 2018 Sep;79(3):514-519. doi: 10.1016/j.jaad.2018.02.067. Epub 2018 Mar 5.
5
Cutaneous manifestations of obesity and themetabolic syndrome.肥胖与代谢综合征的皮肤表现
Clin Dermatol. 2018 Jan-Feb;36(1):81-88. doi: 10.1016/j.clindermatol.2017.09.014. Epub 2017 Sep 8.
6
Incidence of hidradenitis suppurativa among tobacco smokers: a population-based retrospective analysis in the U.S.A.美国基于人群的回顾性分析:吸烟人群中化脓性汗腺炎的发病率
Br J Dermatol. 2018 Mar;178(3):709-714. doi: 10.1111/bjd.15939. Epub 2018 Jan 25.
7
Low and high body mass index in hidradenitis suppurativa patients-different subtypes?患有化脓性汗腺炎的患者中低和高身体质量指数 - 不同的亚型?
J Eur Acad Dermatol Venereol. 2018 Feb;32(2):307-312. doi: 10.1111/jdv.14599. Epub 2017 Oct 10.
8
Factors predicting the self-evaluated health of hidradenitis suppurativa patients recruited from an outpatient clinic.门诊招募的化脓性汗腺炎患者自评健康的预测因素。
J Eur Acad Dermatol Venereol. 2018 Feb;32(2):313-317. doi: 10.1111/jdv.14511. Epub 2017 Oct 11.
9
Hidradenitis Suppurativa in Children Treated with Finasteride-A Case Series.非那雄胺治疗儿童化脓性汗腺炎——病例系列
Pediatr Dermatol. 2017 Sep;34(5):578-583. doi: 10.1111/pde.13216. Epub 2017 Jul 20.
10
Prevalence of hidradenitis suppurativa among patients with Down syndrome: a population-based cross-sectional analysis.患有唐氏综合征的患者中化脓性汗腺炎的患病率:基于人群的横断面分析。
Br J Dermatol. 2018 Mar;178(3):697-703. doi: 10.1111/bjd.15770. Epub 2018 Jan 17.