Ahmed Taghreed Abdel-Rahman, Al-Habbaa Ahmed, Naiem Mona, Mokhtar Naglaa, Elhady Fatma
Cardiology Department, Faculty of Medicine for Girls, Al-Azhar University, Cairo, Egypt.
Cardiology Department, Faculty of Medicine, Al-Azhar University, Cairo, Egypt.
Egypt Heart J. 2024 Sep 12;76(1):124. doi: 10.1186/s43044-024-00560-9.
Globally, Ischemic heart disease (IHD) is considered a leading cause of mortality and morbidity affecting men than women. The more the population ages, the more the prevalence. There was a concern about improper referral of women to MPI testing. We aimed to study if there a gender effect on the results of MPI studies and if this could have an impact on future referral or investigation selection for diagnosis of IHD as a general or specially in women.
Female gender represented 266 (60%) while male represented in 177 (40%). Males demonstrated significantly higher age (55 ± 10 vs. 49 ± 9, P < .0001), weight (85 ± 11 vs. 83 ± 13, P = 0.006), height (166 ± 4 vs. 165 ± 4, P = 0.02), and smoking (35% vs. 0%, P < 0.001) than females. Male gender was associated with ten times increased risk of positive MPI (OR = 10, 95% CI = 5.348-18.868, P < 0.001). Diabetes was associated with an increased risk of positive MPI (OR = 1.82, 95% CI = 1.052-3.148, P = 0.032).
Positive MPI test are more common in males. Female patients with positive MPI were younger in age than male patients. Diabetes mellitus and age are traditional strong predictors for the presence of positive MPI test.
在全球范围内，缺血性心脏病（IHD）被认为是影响男性死亡率和发病率的主要原因，且女性受影响程度低于男性。人口老龄化程度越高，患病率越高。人们担心女性在心肌灌注显像（MPI）检查方面转诊不当。我们旨在研究MPI检查结果是否存在性别差异，以及这是否会对未来IHD诊断的转诊或检查选择产生影响，尤其是对女性的影响。
女性有266例（60%），男性有177例（40%）。男性的年龄（55±10岁 vs. 49±9岁，P<0.0001）、体重（85±11kg vs. 83±13kg，P=0.006）、身高（166±4cm vs. 165±4cm，P=0.02）和吸烟率（35% vs. 0%，P<0.001）均显著高于女性。男性MPI阳性风险增加了10倍（OR=10，95%CI=5.348-18.868，P<0.001）。糖尿病与MPI阳性风险增加相关（OR=1.82，95%CI=1.052-3.148，P=0.032）。
MPI检查阳性在男性中更为常见。MPI检查阳性的女性患者年龄比男性患者小。糖尿病和年龄是MPI检查阳性的传统强预测因素。
