将脂肪体移植到年轻和年老果蝇体内的后果。
The consequences of fat body transplantation into young and old Drosophila.
作者信息
Roberts P A, Iredale R B, Buckley P M
出版信息
Exp Gerontol. 1985;20(2):123-30. doi: 10.1016/0531-5565(85)90048-8.
PMID:3926526
Abstract
Despite some age-related changes in cells, we observed no massive fat body involution during senescence of two species of Drosophila. Transplants of larval fat failed to prolong the life of old D. gibberosa. Transplanted larval fat persisted for weeks and underwent similar changes (except for glycogen stores) in old as in young hosts, suggesting that only minor changes in hemolymph composition occur with age.
摘要
尽管细胞存在一些与年龄相关的变化，但我们在两种果蝇衰老过程中未观察到脂肪体大量退化。幼虫脂肪移植未能延长老年吉氏果蝇的寿命。移植的幼虫脂肪在老年宿主中持续存在数周，并经历了与年轻宿主相似的变化（糖原储备除外），这表明随着年龄增长，血淋巴成分仅发生微小变化。
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