Yovich J L, McColm S C, Yovich J M, Matson P L
Fertil Steril. 1985 Aug;44(2):185-9. doi: 10.1016/s0015-0282(16)48733-9.
In a consecutive series of 167 patients reaching the stage of embryo transfer after in vitro fertilization and embryo transfer, 19 clinical pregnancies ensued. The serum progesterone (P) levels were significantly greater on the first and second (P less than 0.01) and third (P less than 0.05) postaspiration days for those who conceived. Higher circulating levels of P were achieved on days 1, 2, and 3 (P less than 0.05) by the daily injection of P, 50 mg in oil, given for 5 consecutive days, beginning immediately after follicle aspiration. Both pregnancy and nonpregnancy cycles demonstrated high circulating P levels, but the study implies that relatively higher levels are required for conception, and such levels can be achieved by the use of intramuscular P.
在连续的167例接受体外受精和胚胎移植并达到胚胎移植阶段的患者中，有19例临床妊娠。对于受孕的患者，在抽吸后的第1天、第2天（P<0.01）和第3天（P<0.05）血清孕酮（P）水平显著更高。在卵泡抽吸后立即开始，连续5天每天注射50mg油剂P，在第1天、第2天和第3天可使P达到更高的循环水平（P<0.05）。妊娠周期和非妊娠周期的P循环水平都很高，但该研究表明受孕需要相对较高的水平，并且通过肌肉注射P可以达到这样的水平。
