Mitha Rida, Mahan Mark A, Patel Rujvee P, Colan Jhair Alejandro, Leyendecker Jannik, Zaki Mark M, Harake Edward Samir, Kathawate Varun, Kashlan Osama, Konakondla Sanjay, Huang Meng, Elsayed Galal A, Hafez Daniel M, Pennicooke Brenton, Agarwal Nitin, Hofstetter Christoff P, Ogunlade John
Department of Neurosurgery, Washington University School of Medicine, St. Louis, Missouri, USA; Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Department of Neurosurgery, University of Utah, Salt Lake City, Utah, USA.
World Neurosurg. 2024 Nov;191:e644-e651. doi: 10.1016/j.wneu.2024.09.017. Epub 2024 Sep 10.
Degenerative spondylolisthesis is an important cause of chronic low back pain and radiculopathy in the adult U.S.
Open decompression with or without fusion is considered the standard for management, yet optimal treatment remains controversial. Full endoscopic spine surgery offers an alternative surgical approach with possible advantages. There is a paucity of data on the use of full endoscopic spinal surgery in degenerative spondylolisthesis. Therefore, we present the clinical and radiographic outcomes of 73 patients with low-grade degenerative spondylolisthesis with severe stenosis, who underwent lumbar endoscopic unilateral laminectomy for bilateral decompression.
Patients with low-grade degenerative spondylolisthesis who underwent a lumbar endoscopic ULBD at 6 spine centers in North America were included in this study. Patients were followed up at 3, 9, and 12 months. Static and dynamic imaging was performed and evaluated routinely before surgery to identify the pathology and grade of spondylolisthesis. Patient-reported outcomes were prospectively collected.
This study included 73 patients from 6 spine centers. Sixty-two patients were diagnosed with grade I spondylolisthesis, whereas 11 were diagnosed with grade II spondylolisthesis. Postoperatively, 70 patients reported improved symptoms and pain resolution, whereas 3 patients reported worse pain. Mean visual analog scale back and visual analog scale leg scores and Oswestry Disability Index showed a statistically significant improvement at 3, 9, and 12 months compared with the preoperative period. Radiographically, no patient in our study had progression of the grade of spondylolisthesis.
Patients with low-grade degenerative spondylolisthesis causing severe stenosis can safely be treated with lumbar endoscopic unilateral laminectomy for bilateral decompression. A head-to-head trial should be undertaken to provide a higher level of clinical evidence.
退变性腰椎滑脱是美国成年人慢性下腰痛和神经根病的重要原因。
有或没有融合的开放减压术被认为是治疗的标准方法,但最佳治疗方案仍存在争议。全内镜脊柱手术提供了一种具有潜在优势的替代手术方法。关于全内镜脊柱手术在退变性腰椎滑脱中的应用数据较少。因此,我们报告了73例伴有严重狭窄的低度退变性腰椎滑脱患者接受腰椎内镜下单侧椎板切除术进行双侧减压的临床和影像学结果。
本研究纳入了在北美6个脊柱中心接受腰椎内镜下单侧椎板间开窗双侧减压术治疗的低度退变性腰椎滑脱患者。患者在术后3个月、9个月和12个月进行随访。术前常规进行静态和动态影像学检查以确定腰椎滑脱的病理情况和分级。前瞻性收集患者报告的结果。
本研究纳入了来自6个脊柱中心的73例患者。62例患者被诊断为I度腰椎滑脱,11例被诊断为II度腰椎滑脱。术后,70例患者报告症状改善且疼痛缓解,3例患者报告疼痛加重。与术前相比,平均视觉模拟量表背部评分、视觉模拟量表腿部评分和Oswestry功能障碍指数在术后3个月、9个月和12个月均有统计学意义的改善。影像学检查显示,本研究中没有患者出现腰椎滑脱分级进展。
对于因严重狭窄导致的低度退变性腰椎滑脱患者,腰椎内镜下单侧椎板切除术进行双侧减压是一种安全的治疗方法。应进行直接比较的试验以提供更高水平的临床证据。