Manson David, Rutten Caroline
Department of Diagnostic Imaging and Interventional Radiology, The Hospital for Sick Children, 555 University Avenue, Toronto, ON, M5G 1X8, Canada.
Department of Medical Imaging, University of Toronto, Toronto, ON, Canada.
Pediatr Radiol. 2025 Apr;55(4):622-632. doi: 10.1007/s00247-024-06047-8. Epub 2024 Sep 13.
Children with compromised immune systems, whether due to primary or secondary immunodeficiencies, are susceptible to a broad spectrum of acute intrathoracic pathologies. These include infections, pulmonary edema, and malignancies. Pulmonary issues are common and perilous in this population, necessitating prompt and precise diagnosis for effective management. This review aims to provide an overview of such conditions, focusing on the imaging appearances of the most prevalent acute lung conditions affecting immunocompromised children. It emphasizes the critical importance of an integrated clinical and radiological approach when diagnosing these acute pulmonary disease states.
免疫系统受损的儿童,无论其病因是原发性还是继发性免疫缺陷,都易患多种急性胸腔内疾病。这些疾病包括感染、肺水肿和恶性肿瘤。肺部问题在这一人群中很常见且危险,需要及时准确的诊断以进行有效管理。本综述旨在概述此类病症,重点关注影响免疫功能低下儿童的最常见急性肺部疾病的影像学表现。它强调在诊断这些急性肺部疾病状态时,综合临床和放射学方法的至关重要性。