Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, United States.
Front Immunol. 2024 Aug 29;15:1465775. doi: 10.3389/fimmu.2024.1465775. eCollection 2024.
Neuroendocrine neoplasms of the thymus (tNENs), including typical carcinoid, atypical carcinoid, large cell neuroendocrine carcinoma, and small cell carcinoma, are rare tumors with scarce clinical and pathological data available in the literature. They share many common features with neuroendocrine neoplasms in other organs, such as those in the lungs, while demonstrating some distinct clinical and pathological features. This review aims to give an updated overview of each category of tNENs, focusing primarily on the pathologic diagnosis and differential diagnosis of these tumors.
胸腺神经内分泌肿瘤(tNENs)包括典型类癌、不典型类癌、大细胞神经内分泌癌和小细胞癌,是罕见肿瘤,文献中可供参考的临床和病理数据很少。它们与其他器官(如肺部)的神经内分泌肿瘤有许多共同特征,但也表现出一些独特的临床和病理特征。本文旨在对每种 tNEN 进行综述,重点介绍这些肿瘤的病理诊断和鉴别诊断。