Chen Pan, Cheng Junfeng, Zhang Lin
Department of Gynecology, Jinhua Municipal Central Hospital, Jinhua, Zhejiang, China.
Department of Hepatopancreatobiliary Surgery, Jinhua Municipal Central Hospital, Jinhua, Zhejiang, China.
Front Oncol. 2024 Aug 29;14:1448112. doi: 10.3389/fonc.2024.1448112. eCollection 2024.
Melanotic schwannoma (MS), a rare variant of peripheral nerve sheath tumor, is especially infrequent when originating from the peritoneum. Its definitive diagnosis relies on postoperative histopathological examination and immunohistochemical analysis, while preoperative diagnosis is difficult.
In the present study, we reported a rare case of giant MS in the retroperitoneum, which was previously misdiagnosed before surgery. However, intraoperative exploration revealed it was retroperitoneal tumor. The tumor had invaded the abdominal aorta and bilateral common illiac artery walls. A surgical resection was subsequently executed, and postoperative histopathological examination confirmed it as a MS.
The incidence of peritoneal MS is extremely rare, and surgical resection remains the preferred treatment modality. Given the absence of established guidelines for postoperative adjuvant therapy, long-term follow-up becomes imperative to accumulate valuable clinical expertise.
黑色素性神经鞘瘤（MS）是周围神经鞘瘤的一种罕见变异型，起源于腹膜时尤为少见。其明确诊断依赖于术后组织病理学检查和免疫组化分析，而术前诊断困难。
在本研究中，我们报告了一例罕见的腹膜后巨大MS病例，该病例术前曾被误诊。然而，术中探查发现它是腹膜后肿瘤。肿瘤侵犯了腹主动脉和双侧髂总动脉壁。随后进行了手术切除，术后组织病理学检查证实为MS。
腹膜MS的发病率极低，手术切除仍然是首选的治疗方式。鉴于缺乏术后辅助治疗的既定指南，长期随访势在必行，以积累宝贵的临床经验。
