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从愈合到再生：富血小板纤维蛋白在牙周整形手术中的疗效综合综述

From Healing to Regeneration: A Comprehensive Review of the Efficacy of Platelet-Rich Fibrin in Periodontal Plastic Surgery Procedures.

作者信息

Jamjoom Amal G

机构信息

Periodontology Department, Faculty of Dentistry, King Abdulaziz University, Jeddah, SAU.

出版信息

Cureus. 2024 Sep 12;16(9):e69287. doi: 10.7759/cureus.69287. eCollection 2024 Sep.

DOI:10.7759/cureus.69287
PMID:39268023
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11392565/
Abstract

This review examines platelet-rich fibrin (PRF) efficacy in periodontal plastic surgery, highlighting its crucial role in promoting periodontal regeneration and healing. Various forms of PRF are discussed, like leukocyte- and platelet-rich fibrin, advanced PRF, and injectable PRF, in addition to their application in different periodontal procedures such as root coverage and increasing the width of keratinized tissue surrounding the teeth. This review emphasizes the biological benefits of PRF, such as faster wound healing, reduced postsurgical pain, and better management of bleeding. The presence of growth factors, cytokines, and leukocytes in PRF significantly aids in promoting tissue regeneration, thereby improving the clinical outcomes of periodontal therapy. This review also provides recommendations for further research using standardized PRF protocols to optimize the benefits of PRF in clinical practice.

摘要

本综述探讨富血小板纤维蛋白（PRF）在牙周整形手术中的疗效，强调其在促进牙周组织再生和愈合方面的关键作用。文中讨论了各种形式的PRF，如富含白细胞和血小板的纤维蛋白、高级PRF和可注射PRF，以及它们在不同牙周手术中的应用，如牙根覆盖和增加牙齿周围角化组织的宽度。本综述强调了PRF的生物学益处，如更快的伤口愈合、减轻术后疼痛以及更好地控制出血。PRF中生长因子、细胞因子和白细胞的存在显著有助于促进组织再生，从而改善牙周治疗的临床效果。本综述还为进一步研究提供了建议，即使用标准化的PRF方案来优化PRF在临床实践中的益处。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/56b6/11392565/be0893087fe8/cureus-0016-00000069287-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/56b6/11392565/be0893087fe8/cureus-0016-00000069287-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/56b6/11392565/be0893087fe8/cureus-0016-00000069287-i01.jpg

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本文引用的文献

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J Periodontol. 2024 Jul;95(7):632-639. doi: 10.1002/JPER.24-0072. Epub 2024 Jun 17.
2
The effect of platelet-rich fibrin (PRF) versus freeze-dried bone allograft (FDBA) used in alveolar ridge preservation on the peri-implant soft and hard tissues: a randomized clinical trial.富血小板纤维蛋白（PRF）与冻干骨移植物（FDBA）在牙槽嵴保存中对种植体周围软硬组织的影响：一项随机临床试验。
BMC Oral Health. 2024 Jun 14;24(1):693. doi: 10.1186/s12903-024-04478-1.
3
Performance of multiple therapeutic approaches for palatal wound healing after soft tissue graft removal - an overview of systematic reviews.
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Clin Oral Investig. 2024 May 31;28(6):347. doi: 10.1007/s00784-024-05733-z.
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