Gollapudi Monitha, Bajaj Pavan, Oza Ranu R
Periodontology and Implantology, Sharad Pawar Dental College and Hospital, Datta Meghe Institute of Medical Sciences, Wardha, IND.
Periodontics and Implantology, Sharad Pawar Dental College and Hospital, Datta Meghe Institute of Medical Sciences, Wardha, IND.
Cureus. 2022 Aug 31;14(8):e28647. doi: 10.7759/cureus.28647. eCollection 2022 Aug.
As of a few years ago, platelet concentrates have been applied in a variety of medical and dental procedures. A notable aspect is that platelet-rich fibrin (PRF) is the most commonly utilized platelet concentrate in the field of dentistry. The most significant modification that was used over the years but had the biggest impact was injectable platelet-rich fibrin (I-PRF), which has more special properties. Additionally, the results of this I-PRF have been useful. The solid platelet-rich fibrin (PRF), which is a noticeable feature and has a low speed and duration in centrifugation, is the main advantage of I-PRF. I-PRF is primarily found in liquid form as PRF. It facilitates the quickening of increased vascularization and aids in accelerating the healing of wounds. An autologous blood concentration known as I-PRF has been known for many years. The advantage of I-PRF is that it exhibits constant release of growth factors and promotes cell migration by announcing the expression of type I collagen and transforming growth factor mRNA. The majority of the time, plastic and orthopedic operations use injectable platelet aggregates. It also reduces adverse reactions to transplanted material as compared to other grafting techniques. Additionally, it makes numerous other operations, like regenerative ones, much better options. In circumstances where it has been noticed, I-PRF is helpful and crucial in periodontics for bone regeneration and wound healing. It is therefore not difficult to predict that this fully autologous blood concentrate, which is now being utilized in numerous applications and requires little invasiveness, will become even more frequently used in the future. This review paper contains the differences between platelet-rich plasma (PRP) and PRF, the development of diverse platelets, and the use of I-PRF in periodontal therapy.
几年前，血小板浓缩物已应用于各种医学和牙科手术。一个值得注意的方面是，富血小板纤维蛋白（PRF）是牙科领域最常用的血小板浓缩物。多年来使用的最显著且影响最大的改进是可注射富血小板纤维蛋白（I-PRF），它具有更特殊的性质。此外，I-PRF的效果很显著。固体富血小板纤维蛋白（PRF）是I-PRF的主要优点，这是一个显著特征，其离心速度慢且持续时间短。I-PRF主要以PRF的液体形式存在。它有助于加快血管生成，并促进伤口愈合。I-PRF作为一种自体血液浓缩物已为人所知多年。I-PRF的优点是它能持续释放生长因子，并通过促进I型胶原蛋白和转化生长因子mRNA的表达来促进细胞迁移。大多数情况下，整形和骨科手术使用可注射血小板聚集体。与其他移植技术相比，它还能减少对移植材料的不良反应。此外，它使许多其他手术，如再生手术，成为更好的选择。在已被注意到的情况下，I-PRF在牙周病学中对骨再生和伤口愈合很有帮助且至关重要。因此不难预测，这种目前正在众多应用中使用且侵入性小的完全自体血液浓缩物，未来将更频繁地被使用。这篇综述文章包含了富血小板血浆（PRP）和PRF之间的差异、不同血小板的发展以及I-PRF在牙周治疗中的应用。
