van der Ven Eva, Patra Stefan, Riemann-Lorenz Karin, Kauschke Katrin, Freese-Schwarz Katrin, Welsch Götz, Krause Nicole, Heesen Christoph, Rosenkranz Sina Cathérine
Institute of Neuroimmunology and Multiple Sclerosis (INIMS), University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Department of Neurology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Front Neurol. 2024 Aug 23;15:1428712. doi: 10.3389/fneur.2024.1428712. eCollection 2024.
Despite the evidence of beneficial effects of physical activity (PA), people with multiple sclerosis (pwMS) are less physically active than the general population. To increase PA in pwMS, we developed a structured individually tailored PA promotion program which is conducted within clinical practice in a university-based outpatient clinic since 2016. This study serves as retrospective quality control of this program.
In a retrospective cohort study, we assessed the physical fitness of pwMS and the impact of the program on short- and long-term PA changes and behavioral determinants.
The program consisted of four appointments each 2-4 weeks apart. Spiroergometric test results of female pwMS were compared to female non-MS controls who underwent a voluntary physical fitness analysis. The short version of the Freiburger questionnaire, self-developed questions and the modified Physical activity screening questionnaire (PASQ) were sent to all participants assessing the PA levels before the program, 3 months after the program (short-term), and at the time of the survey (long-term). Additionally, established questionnaires assessed behavioral determinants before the program and long-term.
A total of 166 participants [mean age 38.32 (± 10.61 SD), mean EDSS 2.30 (±1.29 SD)] and mostly females (63.3%, = 105) were included in the study and started the program. A total of 136 participants completed the program. Out of these 63.9% ( = 87) answered the questionnaires in 12.38 (±11.34 SD) months after finishing the program. At baseline female pwMS ( = 100) showed a lower physical fitness in comparison to non-MS controls ( = 26) (maximal workload (Watts): 138.86 ± 37.85 vs. 191.73 ± 45.25, < 0.001; peak oxygen consumption (ml min kg): 26.40 ± 7.23 vs. 31.56 ± 10.10, = 0.020). pwMS were more regularly active in short- (62.1%) and long-term (55.2%) compared to baseline (24.2%, < 0.001). Among the activated participants, we observed improved internal motivation ( = 0.002) and decreased perception of barriers ( = 0.006) compared to baseline.
PwMS showed a lower physical fitness in comparison to non-MS controls. An individually tailored PA promotion program might improve behavioral determinants and thereby increase short- and long-term PA levels of pwMS.
尽管有证据表明体育活动（PA）具有有益效果，但多发性硬化症患者（pwMS）的身体活动水平低于普通人群。为了提高pwMS的体育活动水平，我们自2016年起在一所大学附属医院的门诊临床实践中制定并实施了一项结构化的个性化体育活动促进计划。本研究旨在对该计划进行回顾性质量控制。
在一项回顾性队列研究中，我们评估了pwMS的身体素质以及该计划对短期和长期体育活动变化及行为决定因素的影响。
该计划包括四次预约，每次间隔2 - 4周。将女性pwMS的运动心肺功能测试结果与接受自愿体能分析的非MS女性对照进行比较。向所有参与者发送了弗赖堡问卷的简短版本、自行设计的问题以及改良的体育活动筛查问卷（PASQ），以评估计划实施前、计划实施后3个月（短期）和调查时（长期）的体育活动水平。此外，使用既定问卷评估计划实施前和长期的行为决定因素。
共有166名参与者[平均年龄38.32（±10.61标准差），平均扩展残疾状态量表（EDSS）2.30（±1.29标准差）]纳入研究并开始该计划，其中大多数为女性（63.3%，n = 105）。共有136名参与者完成了该计划。在这些参与者中，63.9%（n = 87）在完成计划后的12.38（±11.34标准差）个月内回答了问卷。在基线时，与非MS对照（n = 26）相比，女性pwMS（n = 100）的身体素质较低（最大工作量（瓦特）：138.86 ± 37.85 vs. 191.73 ± 45.25，P < 0.001；峰值耗氧量（毫升·分钟·千克）：26.40 ± 7.23 vs. 31.56 ± 10.10，P = 0.020）。与基线（24.2%，P < 0.001）相比，pwMS在短期（62.1%）和长期（55.2%）的体育活动更为规律。在活跃的参与者中，与基线相比，我们观察到内在动机有所改善（P = 0.002），对障碍的感知有所降低（P = 0.006）。
与非MS对照相比，pwMS的身体素质较低。一项个性化的体育活动促进计划可能会改善行为决定因素，从而提高pwMS的短期和长期体育活动水平。
