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严重急性呼吸综合征冠状病毒2感染加重膈膨出:一例报告

SARS‑CoV‑2 infection exacerbates diaphragmatic eventration: A case report.

作者信息

Xu Tao, Yu Wanjun

机构信息

Department of Respiratory and Critical Care Medicine, The Affiliated People's Hospital of Ningbo University, Ningbo, Zhejiang 315040, P.R. China.

出版信息

Biomed Rep. 2024 Aug 27;21(5):157. doi: 10.3892/br.2024.1845. eCollection 2024 Nov.

Abstract

Adult congenital localized diaphragmatic eventration (DE) is an uncommon condition that, due to the absence of notable symptoms, is often ignored and is consequently not frequently treated following diagnosis. Furthermore, the progression of localized DE into complete DE is rare. The recent coronavirus disease 2019 pandemic has placed a strain on global health care systems, including those in China, and exacerbated several underlying medical complications and diseases. This has resulted in a rapid progression of underlying diseases and even death in cases of diabetes or pre-existing respiratory diseases and other chronic conditions. The present study describes the case of a patient with congenital localized DE that progressed to complete DE following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The patient had a medical history of localized DE with persistent cough, chest tightness and abdominal distension following infection with SARS-CoV-2. Chest X-ray and computed tomography examinations confirmed the diagnosis of complete DE on the left side. Therefore, the patient underwent thoracic surgery for left-sided diaphragmatic plication. At the 6-month follow-up visit, the patient had recovered well and did not show any complications. Overall, the present study demonstrated that SARS-CoV-2 infection exacerbated the progression of left-sided congenital localized DE, which had no obvious symptoms, to complete DE accompanied by severe symptoms.

摘要

成人先天性局限性膈膨升(DE)是一种罕见疾病,由于缺乏明显症状,常被忽视,因此确诊后往往得不到及时治疗。此外,局限性DE进展为完全性DE的情况很少见。最近的2019冠状病毒病大流行给包括中国在内的全球医疗系统带来了压力,加剧了一些潜在的医疗并发症和疾病。这导致了基础疾病的快速进展,在糖尿病或原有呼吸系统疾病及其他慢性病患者中甚至导致死亡。本研究描述了1例先天性局限性DE患者在感染严重急性呼吸综合征冠状病毒2(SARS-CoV-2)后进展为完全性DE的病例。该患者有局限性DE病史,感染SARS-CoV-2后出现持续咳嗽、胸闷和腹胀。胸部X线和计算机断层扫描检查确诊为左侧完全性DE。因此,该患者接受了左侧膈肌折叠术的胸外科手术。在6个月的随访中,患者恢复良好,未出现任何并发症。总体而言,本研究表明,SARS-CoV-2感染加剧了左侧先天性局限性DE(无明显症状)向伴有严重症状的完全性DE的进展。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3c57/11391511/cc49537cbe5c/br-21-05-01845-g00.jpg

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