Dumbre Dipali U, Devi Seeta, Chavan Ranjana G
Symbiosis College of Nursing, Symbiosis International (Deemed University), Pune, Maharashtra, India.
J Educ Health Promot. 2024 Jul 5;13:164. doi: 10.4103/jehp.jehp_41_24. eCollection 2024.
The scoping review aimed to investigate and compile the effects of antibiotics on children under the age of five's physiological development. A PubMed, CINAHL, and Medline online database search was conducted, and related studies were included in the databases to carry out a more detailed search of the available literature utilizing keywords like "Antibiotics in children's"; "Children under 5"; and "Physiological Development, Physical Development," as well as Boolean operators to generate papers pertinent which were correlating with the objective of the study. It is imperative to demonstrate that a comprehensive, wide-ranging, and exhaustive search was carried out. MeSH words used for the search. MeSH is an is an effective tool for indexing and classifying literature on biology and health. MeSH terms are affixed to articles to enable precise and effective literature searches, guaranteeing that scholars, medical professionals, and other users can locate pertinent data within the extensive PubMed database. MeSH provides researchers with a standardized and structured method of indexing topics in the field of medicine and related disciplines, which aids in the identification and organization of pertinent articles during scoping reviews. PRISMA checklist was followed while doing the data collection and data extraction. The findings revealed that antibiotics hurt the physical and physiological development of children under 5. The study findings show that after exposure to antibiotics children get obese, it also affects the gut microbiota. Antibiotics also have an impact on the language and behaviors of children under 5. It also shows that children are more prone to get different medical disorders. These results highlight how crucial it is to make well-informed decisions about the use of antibiotics in pediatric care. To sum up, giving antibiotics to kids younger than five can have a big impact on how their bodies develop. This study also provides and implements guidelines that consider the possible long-term effects on the development of children under the age of five when prescribing antibiotics. Encourage healthcare professionals, parents, and other caregivers to learn about the proper use of antibiotics for young children as well as the possible risks of overusing or not using antibiotics at all. Promote funding and research for alternative approaches, such as targeted vaccines or probiotics, to treat and prevent infections in young children.
这项范围综述旨在调查和汇编抗生素对五岁以下儿童生理发育的影响。我们在PubMed、CINAHL和Medline在线数据库中进行了搜索,并将相关研究纳入数据库,利用“儿童抗生素”“五岁以下儿童”“生理发育、身体发育”等关键词以及布尔运算符进行更详细的可用文献搜索,以生成与研究目标相关的论文。必须证明进行了全面、广泛且详尽的搜索。搜索使用了医学主题词(MeSH)。MeSH是对生物学和健康文献进行索引和分类的有效工具。MeSH术语附加在文章上,以便进行精确有效的文献搜索,确保学者、医学专业人员和其他用户能够在庞大的PubMed数据库中找到相关数据。MeSH为研究人员提供了一种在医学及相关学科领域对主题进行索引的标准化和结构化方法,有助于在范围综述期间识别和组织相关文章。在进行数据收集和数据提取时遵循了系统评价和Meta分析的首选报告项目(PRISMA)清单。研究结果显示,抗生素会损害五岁以下儿童的身体和生理发育。研究结果表明,接触抗生素后儿童会肥胖,这也会影响肠道微生物群。抗生素还会对五岁以下儿童的语言和行为产生影响。研究还表明,儿童更容易患上各种疾病。这些结果凸显了在儿科护理中对抗生素使用做出明智决策的重要性。总之,给五岁以下的儿童使用抗生素会对他们的身体发育产生重大影响。本研究还提供并实施了指导方针,在开具抗生素处方时考虑对五岁以下儿童发育可能产生的长期影响。鼓励医疗保健专业人员、家长和其他照顾者了解幼儿抗生素的正确使用方法以及过度使用或完全不使用抗生素可能存在的风险。促进对替代方法(如靶向疫苗或益生菌)的资金投入和研究,以治疗和预防幼儿感染。