Proietti Francesca, Pontani Martina, Pepe Alessio, Magliozzi Alessandro, Toro Stefano, Anzini Gaia, Albergo Giuliano, Ricciuti Riccardo, Di Lazzaro Vincenzo, Marano Massimo
Operative Research Unit of Neurology, Neurophysiology, Neurobiology and Psychiatry, Department of Medicine, Università Campus Bio-Medico di Roma, Rome, Italy.
UOSD Neurology, Isola Tiberina Hospital, Rome, Italy.
Neurol Sci. 2025 Jan;46(1):157-164. doi: 10.1007/s10072-024-07753-9. Epub 2024 Sep 13.
Parkinson's disease patients may experience altered body image perception. Advanced Parkinson's disease (aPD) with motor complications often requires surgical and device-aided treatments (DAT), such as levodopa-carbidopa intestinal gel (LCIG) and deep brain stimulation (DBS). Understanding body image perception is crucial when managing these devices. This study aims to explore body image perception in aPD patients, hypothesizing a link between DAT and body image perception.
We performed a cross-sectional study including non-demented aPD patients with and without DAT and age- and sex-matched controls. Participants were assessed using the Appearance Schemas Inventory-Revised (ASI-R), including Motivational Salience (MS) and Self-Evaluative Salience (SES) scores. Additional data included age, education, BMI, comorbidities, pharmacotherapy, and psychopathologies. PD patients were also evaluated with UPDRS, Hoehn and Yahr scales and LEDD calculation.
70 aPD and 36 controls were enrolled. No differences in ASI-R scores were found between PD patients and controls, but women with PD had significantly lower MS scores than controls (16.1 ± 5.6 vs 19.7 ± 5.8; p = 0.023). Among aPD patients, those on DAT had longer disease duration, higher Hoehn and Yahr, and lower UPDRS IV scores. The lowest MS was observed in women on LCIG (12.7 ± 3.3; p = 0.001).
This study shows low MS ratings driven by female gender and LCIG treatment. Women on LCIG show reduced attention and management of their appearance. This may be influenced by cultural, environmental, and biological factors. Prospective research is needed to understand the impact of DAT on body image.
帕金森病患者可能会出现身体形象感知改变。伴有运动并发症的晚期帕金森病（aPD）通常需要手术和设备辅助治疗（DAT），如左旋多巴 - 卡比多巴肠凝胶（LCIG）和脑深部电刺激（DBS）。在管理这些设备时，了解身体形象感知至关重要。本研究旨在探讨aPD患者的身体形象感知，假设DAT与身体形象感知之间存在联系。
我们进行了一项横断面研究，纳入了有或无DAT的非痴呆aPD患者以及年龄和性别匹配的对照组。使用修订后的外表图式量表（ASI - R）对参与者进行评估，包括动机显著性（MS）和自我评估显著性（SES）得分。其他数据包括年龄、教育程度、体重指数、合并症、药物治疗和精神病理学。还使用统一帕金森病评定量表（UPDRS）、霍恩和雅尔分级量表以及左旋多巴等效剂量（LEDD）计算对PD患者进行评估。
共纳入70例aPD患者和36例对照组。PD患者和对照组之间在ASI - R得分上未发现差异，但患有PD的女性的MS得分显著低于对照组（16.1±5.6对19.7±5.8；p = 0.023）。在aPD患者中，接受DAT治疗的患者病程更长，霍恩和雅尔分级更高，UPDRS IV得分更低。接受LCIG治疗的女性的MS得分最低（12.7±3.3；p = 0.001）。
本研究表明女性性别和LCIG治疗导致MS评分较低。接受LCIG治疗的女性对外表的关注和管理减少。这可能受到文化、环境和生物学因素的影响。需要进行前瞻性研究以了解DAT对身体形象的影响。
