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糖尿病、血脂异常和心血管疾病 2.0 中的新型分子

Novel Molecules in Diabetes Mellitus, Dyslipidemia and Cardiovascular Disease 2.0.

机构信息

Department of Preclinical Disciplines, Faculty of Medicine and Pharmacy, University of Oradea, 410073 Oradea, Romania.

Doctoral School of Biomedical Sciences, University of Oradea, 410087 Oradea, Romania.

出版信息

Int J Mol Sci. 2024 Sep 2;25(17):9527. doi: 10.3390/ijms25179527.

DOI:10.3390/ijms25179527
PMID:39273474
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11394761/
Abstract

Diabetes mellitus, dyslipidemia and cardiovascular disorders represent very prevalent chronic diseases in developed countries contributing to a high morbidity and loss of quality of life [...].

摘要

糖尿病、血脂异常和心血管疾病是发达国家非常普遍的慢性病,导致高发病率和生活质量下降[...]。

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Novel Molecules in Diabetes Mellitus, Dyslipidemia and Cardiovascular Disease 2.0.糖尿病、血脂异常和心血管疾病 2.0 中的新型分子
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本文引用的文献

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Do SGLT2 inhibitors and GLP-1 receptor agonists modulate differently the risk of stroke ? Discordance between randomised controlled trials and observational studies.钠-葡萄糖协同转运蛋白 2(SGLT2)抑制剂和胰高血糖素样肽 1(GLP-1)受体激动剂是否能调节卒中风险?随机对照试验与观察性研究之间的差异。
Diabetes Metab. 2023 Sep;49(5):101474. doi: 10.1016/j.diabet.2023.101474. Epub 2023 Sep 5.
2
Novel Antidiabetic Agents and Their Effects on Lipid Profile: A Single Shot for Several Cardiovascular Targets.新型抗糖尿病药物及其对血脂谱的影响:一箭多雕的心血管治疗靶点。
Int J Mol Sci. 2023 Jun 15;24(12):10164. doi: 10.3390/ijms241210164.
3
Cardiovascular Risk and Statin Therapy Considerations in Women.女性心血管风险与他汀类药物治疗考量
Diagnostics (Basel). 2020 Jul 16;10(7):483. doi: 10.3390/diagnostics10070483.
4
An investigation into the pleiotropic activity of metformin. A glimpse of haemostasis.探究二甲双胍的多效性活性。对止血作用的一瞥。
Eur J Pharmacol. 2020 Apr 5;872:172984. doi: 10.1016/j.ejphar.2020.172984. Epub 2020 Feb 1.
5
Glucose Lowering Efficacy and Pleiotropic Effects of Sodium-Glucose Cotransporter 2 Inhibitors.钠-葡萄糖共转运蛋白 2 抑制剂的降糖疗效和多效作用。
Adv Exp Med Biol. 2021;1307:213-230. doi: 10.1007/5584_2020_479.
6
Pleiotropic Effects of GLP-1 and Analogs on Cell Signaling, Metabolism, and Function.胰高血糖素样肽-1及其类似物对细胞信号传导、代谢和功能的多效性作用
Front Endocrinol (Lausanne). 2018 Nov 23;9:672. doi: 10.3389/fendo.2018.00672. eCollection 2018.
7
Pleiotropic Anti-atherosclerotic Effects of PCSK9 InhibitorsFrom Molecular Biology to Clinical Translation.PCSK9 抑制剂的多效抗动脉粥样硬化作用:从分子生物学到临床转化。
Curr Atheroscler Rep. 2018 Mar 10;20(4):20. doi: 10.1007/s11883-018-0718-x.
8
Incretins yesterday, pleiotropic gastrointestinal hormones today:glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP).昨日的肠促胰岛素,今日的多效性胃肠激素:胰高血糖素样肽-1(GLP-1)和葡萄糖依赖性促胰岛素多肽(GIP)。
Recent Pat Endocr Metab Immune Drug Discov. 2011 Sep;5(3):176-82. doi: 10.2174/187221411797265863.