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复发性静脉疾病患者比未接受过先前干预的患者从序贯治疗中获益更多吗?一项关于腹部和盆腔静脉栓塞序贯治疗安全性和有效性的单中心回顾性研究。

May Patients with Recurrent Venous Disease Benefit from Sequential Treatment More than Those without Previous Intervention? A Single-Center Retrospective Study on the Safety and Efficacy of Abdominal and Pelvic Veins Embolization in Sequential Approach.

作者信息

Szary Cezary, Wilczko-Kucharska Justyna, Celejewski Krzysztof, Łodyga Małgorzata, Napierala Marcin, Plucinska Dominika, Swieczkowski-Feiz Siavash, Leszczynski Jerzy, Zawadzki Michal, Grzela Tomasz

机构信息

Clinic of Phlebology, 02-034 Warsaw, Poland.

Department of General, Endocrinological and Vascular Surgery, Central University Hospital, Medical University of Warsaw, 02-091 Warsaw, Poland.

出版信息

J Clin Med. 2024 Aug 26;13(17):5053. doi: 10.3390/jcm13175053.

DOI:10.3390/jcm13175053
PMID:39274266
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11396737/
Abstract

The endovenous embolization of insufficient abdominal/pelvic veins is the preferred method of treatment. Also, it seems to be crucial in the treatment of lower limb vein insufficiency, particularly in recurrent disease. This study aimed to evaluate of pelvic vein embolization safety and its impact on the short-term outcome in the sequential treatment of venous disease. A retrospective analysis involved data from 506 female patients with venous disease involving abdominal and pelvic veins. All records were extracted from the medical database and included patient history, imaging reports as well as pre- and post-operative surveys. Among the patients analyzed, 37.2% underwent some venous intervention in the past, with significant differences in symptom severity between groups. The embolization procedure revealed a high safety profile, with no serious complications. Pain during and after the procedure was generally low, with significantly lower pain scores in patients with recurrence. In patients who required left renal vein venoplasty a 1.7-fold increased risk of lumbar pain after embolization and venoplasty procedure was observed. Overall, 66.6% of patients reported improvement in pelvic symptoms and 72.1% experienced improvement in leg symptoms. The full sequential treatment protocol (abdominal, pelvic, and leg compartment) demonstrated superior outcomes in leg symptom improvement compared to embolization alone. Pelvic vein embolization is a safe and effective method of treatment, significantly improving both pelvic and leg symptoms, particularly in patients with a history of previous interventions in lower limb veins. Further studies are warranted to validate our findings and further refine treatment protocols.

摘要

腹部/盆腔静脉功能不全的腔内栓塞是首选治疗方法。此外,它在下肢静脉功能不全的治疗中似乎至关重要,尤其是在复发性疾病中。本研究旨在评估盆腔静脉栓塞的安全性及其对静脉疾病序贯治疗短期结果的影响。一项回顾性分析纳入了506例患有腹部和盆腔静脉疾病的女性患者的数据。所有记录均从医疗数据库中提取,包括患者病史、影像学报告以及术前和术后调查。在分析的患者中,37.2%过去曾接受过一些静脉干预,各组间症状严重程度存在显著差异。栓塞手术显示出较高的安全性,无严重并发症。手术期间及术后疼痛一般较轻,复发患者的疼痛评分显著更低。在需要进行左肾静脉血管成形术的患者中,观察到栓塞和血管成形术后腰痛风险增加1.7倍。总体而言,66.6%的患者报告盆腔症状有所改善,72.1%的患者腿部症状有所改善。完整的序贯治疗方案(腹部、盆腔和腿部)在改善腿部症状方面比单纯栓塞显示出更好的效果。盆腔静脉栓塞是一种安全有效的治疗方法,能显著改善盆腔和腿部症状,尤其是有下肢静脉既往干预史的患者。有必要进行进一步研究以验证我们的发现并进一步完善治疗方案。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0070/11396737/1d105f1ad1b5/jcm-13-05053-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0070/11396737/560f838fec32/jcm-13-05053-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0070/11396737/30e4c76cea37/jcm-13-05053-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0070/11396737/9f7d31202ac1/jcm-13-05053-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0070/11396737/188ec4a5f620/jcm-13-05053-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0070/11396737/684375c0857d/jcm-13-05053-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0070/11396737/1d105f1ad1b5/jcm-13-05053-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0070/11396737/560f838fec32/jcm-13-05053-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0070/11396737/30e4c76cea37/jcm-13-05053-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0070/11396737/9f7d31202ac1/jcm-13-05053-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0070/11396737/188ec4a5f620/jcm-13-05053-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0070/11396737/684375c0857d/jcm-13-05053-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0070/11396737/1d105f1ad1b5/jcm-13-05053-g006.jpg

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Surgical and endovascular treatment of pelvic venous disorder: Results of a multicentre retrospective cohort study.盆腔静脉疾病的手术和血管内治疗:多中心回顾性队列研究结果。
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