Scientific and Educational Center 'Biomedical Technologies', School of Medical Biology, South Ural State University, 454080 Chelyabinsk, Russia.
Zelman Institute of Medicine and Psychology, Novosibirsk State University, 630090 Novosibirsk, Russia.
Nutrients. 2024 Aug 26;16(17):2856. doi: 10.3390/nu16172856.
The medicinal properties of resveratrol have garnered increasing attention from researchers. Extensive data have been accumulated on its use in treating cardiovascular diseases, immune system disorders, cancer, neurological diseases, and behavioral disorders. The protective mechanisms of resveratrol, particularly in anxiety-related stress disorders, have been well documented. However, less attention has been given to the side effects of resveratrol. This review explores not only the mechanisms underlying the anxiolytic effects of resveratrol but also the mechanisms that may lead to increased anxiety following resveratrol treatment. Understanding these mechanisms is crucial for enhancing the efficacy of resveratrol in managing anxiety disorders associated with stress and PTSD.
白藜芦醇的药用特性引起了研究人员越来越多的关注。关于它在治疗心血管疾病、免疫系统紊乱、癌症、神经疾病和行为障碍方面的应用，已经积累了大量的数据。白藜芦醇的保护机制，特别是在与焦虑相关的应激障碍方面，已经有充分的记录。然而，人们对其副作用的关注较少。本综述不仅探讨了白藜芦醇抗焦虑作用的机制，还探讨了白藜芦醇治疗后可能导致焦虑增加的机制。了解这些机制对于提高白藜芦醇治疗与应激和 PTSD 相关的焦虑障碍的疗效至关重要。
