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经导管动脉栓塞术治疗产后HELLP综合征:一例报告

Transcatheter arterial embolization in postpartum HELLP syndrome: A case report.

作者信息

Zhou Xusheng, Shi Qi, Xie Zhijiang, Wang Lei, Gao Liuqin, Dai Jiaying

机构信息

Department of Interventional Radiology, Anqing Municipal Hospital, Anqing 246000, Anhui, China.

Department of Gynaecology and Obstetrics, Anqing Municipal Hospital, Anqing 246000, Anhui, China.

出版信息

Int J Surg Case Rep. 2024 Oct;123:110291. doi: 10.1016/j.ijscr.2024.110291. Epub 2024 Sep 12.

Abstract

INTRODUCTION

Hemolysis, elevated liver enzyme levels, and low platelet count (HELLP) syndrome is a pregnancy-related clinical condition characterized by hemolysis, elevated liver enzymes, and thrombocytopenia, posing significant risks to maternal and fetal safety. Hepatic hematoma with spontaneous rupture and bleeding is a rare but severe complication of HELLP syndrome, with limited reports of hepatic artery intervention and embolization therapy.

PRESENTATION OF CASE

We present the case of a 35-year-old pregnant woman who developed worsening pain under the xiphoid process the night following a cesarean section. Her blood pressure dropped from 189/110 mmHg to 90/60 mmHg within 40 min. Vaginal exploration revealed no blood flow, and subsequent laparotomy uncovered multiple small liver surface lacerations actively bleeding. Emergency transcatheter arterial embolization (TAE) was promptly performed, stabilizing her condition. She was discharged 37 days post-admission.

DISCUSSION

TAE plays an important role in the treatment of HELLP syndrome with spontaneous liver rupture, with characteristics of minimal trauma and good efficacy, but the evidence supporting this recommendation is somewhat limited.

CONCLUSION

This case underscores TAE as a potentially effective and less invasive alternative to surgical interventions for managing HELLP syndrome with spontaneous liver rupture. Further research is needed to better clarify the safety and efficacy of TAE in the treatment of HELLP syndrome with spontaneous liver rupture.

摘要

引言

溶血、肝酶升高和血小板减少(HELLP)综合征是一种与妊娠相关的临床病症,其特征为溶血、肝酶升高和血小板减少,对母婴安全构成重大风险。肝血肿伴自发破裂出血是HELLP综合征罕见但严重的并发症,关于肝动脉介入和栓塞治疗的报道有限。

病例介绍

我们报告一例35岁的剖宫产术后当晚剑突下疼痛加重的孕妇。她的血压在40分钟内从189/110mmHg降至90/60mmHg。阴道检查未发现血流,随后剖腹探查发现肝脏表面多处小裂伤并伴有活动性出血。紧急进行了经导管动脉栓塞术(TAE),使她的病情稳定下来。她在入院37天后出院。

讨论

TAE在治疗伴有自发性肝破裂的HELLP综合征中发挥着重要作用,具有创伤小、疗效好的特点,但支持这一建议的证据较为有限。

结论

该病例强调TAE作为治疗伴有自发性肝破裂的HELLP综合征的一种潜在有效且侵入性较小的手术干预替代方法。需要进一步研究以更好地阐明TAE在治疗伴有自发性肝破裂的HELLP综合征中的安全性和疗效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/046c/11418135/116a6f60c8ba/gr1.jpg

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