Department of Orthodontics and Dentofacial Orthopaedics, Amrita School of Dentistry, Amrita Vishwa Vidyapeetham, kochi, Kerala, India
Department of Public Health Dentistry, Amrita School of Dentistry, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India.
BMJ Open. 2024 Sep 13;14(9):e082396. doi: 10.1136/bmjopen-2023-082396.
The review involves the assessment of morphological variations in the temporomandibular joint (TMJ) and its associated structures in patients with temporomandibular disorder.
Temporomandibular disorders (TMD) are debilitating conditions that affect the TMJ complex, surrounding musculature and osseous components. Studies have reported that TMD result from morphological alterations in TMJ. These alterations can be efficiently studied using three-dimensional imaging. This review will summarise the morphological changes in TMJ and associated structures based on studies with three-dimensional imaging in patients with TMD.
The systematic review will include studies with adult subjects with any one symptom of TMD and those studies that assessed TMJ morphology using three-dimensional imaging like CT, cone beam CT, MRI or arthrography.
Systematic searches for relevant studies will be carried out in multiple databases. Sources will include MEDLINE, Scopus, Dentistry and Oral Sciences Source, Cochrane CENTRAL, CINAHL, Web of Science, ProQuest Dissertation and Thesis and Google Scholar. The databases will be searched from inception to November 2023. Analytical observational studies comprising retrospective and prospective cohort studies, case-control studies and analytical cross-sectional studies will be selected and critical appraisal will be performed. No restrictions will be imposed on the date and country of publication. Joanna Briggs Institute (JBI) guidelines for systematic effectiveness reviews will be followed for data appraisal, extraction and synthesis. The strength of evidence will be graded using the Grading of Recommendations, Assessment, Development and Evaluation method and the summary of findings will be created using GRADEpro software.
Ethical approval is not applicable for this study since this involves analysis of secondary data. Results will be disseminated through peer-reviewed publications and cnference presentations. A comprehensive summary of morphological alterations in TMJ is essential for assessing risk factors, accurate diagnosis, treatment planning and will collectively contribute to enhanced clinical care and overall patient well-being.
The protocol is registered in PROSPERO: CRD42023448882.
本综述评估了颞下颌关节（TMJ）及其相关结构在颞下颌关节紊乱患者中的形态学变化。
颞下颌关节紊乱（TMD）是一种使人衰弱的疾病，影响 TMJ 复合体、周围肌肉和骨骼成分。研究报告称，TMD 是由 TMJ 的形态改变引起的。这些改变可以通过三维成像进行有效研究。本综述将根据 TMD 患者的三维成像研究，总结 TMJ 及相关结构的形态变化。
本系统综述将包括任何一种 TMD 症状的成年患者的研究，以及使用三维成像（如 CT、锥形束 CT、MRI 或关节造影）评估 TMJ 形态的研究。
将在多个数据库中进行相关研究的系统检索。来源包括 MEDLINE、Scopus、牙科学和口腔科学源、Cochrane 中央、CINAHL、Web of Science、ProQuest 论文和论文以及 Google Scholar。数据库将从创建到 2023 年 11 月进行搜索。将选择分析性观察研究，包括回顾性和前瞻性队列研究、病例对照研究和分析性横断面研究，并进行批判性评价。不限制研究的日期和国家。将遵循乔安娜·布里格斯研究所（JBI）的系统有效性评价指南进行数据评价、提取和综合。使用推荐、评估、发展和评估方法（GRADE）对证据的强度进行分级，并使用 GRADEpro 软件创建研究结果总结。
本研究不需要伦理批准，因为这涉及对二次数据的分析。结果将通过同行评议的出版物和会议报告进行传播。全面总结 TMJ 的形态改变对于评估危险因素、准确诊断、治疗计划至关重要，并将共同促进临床护理的提高和患者整体福祉。
PROSPERO 注册号：本方案已在 PROSPERO 注册：CRD42023448882。
