State Key Laboratory of Crop Stress Resistance and High-Efficiency Production, College of Plant Protection, Northwest A&F University, Yangling 712100, Shaanxi, China.
Key Laboratory of Plant Protection Resources and Pest Management of Ministry of Education, Key Laboratory of Integrated Pest Management on Crops in Northwestern Loess Plateau of Ministry of Agriculture and Rural Affairs, College of Plant Protection, Northwest A&F University, Yangling 712100, Shaanxi, China.
Pestic Biochem Physiol. 2024 Sep;204:106085. doi: 10.1016/j.pestbp.2024.106085. Epub 2024 Aug 13.
Fluoxapiprolin, a novel piperidinyl thiazole isoxazoline fungicide, was developed by Bayer Crop Science in 2012. Despite its well-documented inhibitory activity against plant pathogenic oomycetes such as Phytophthora capsici and Phytophthora infestans, limited information regarding its antifungal spectrum and protective and curative activity is available. Fluoxapiprolin exhibited strong inhibitory activity against Phytophthora spp. and several Pythium spp., with EC values ranging from 2.12 × 10 to 2.92 μg/mL. It was much more effective against P. capsici in inhibiting mycelial growth, sporangium production, and cystospore germination than at reducing zoospore release. Moreover, fluoxapiprolin displayed both protective and curative activity against P. capsici infection in pepper plants under greenhouse conditions, with systemic translocation capability confirmed by High Performance Liquid Chromatography (HPLC) analysis. The results demonstrated the strong inhibitory activity of fluoxapiprolin against economically important plant oomycete pathogens, including Phytophthora spp. and several Pythium spp., and its certain translocation activity in pepper plants.
氟吡菌酰胺，一种新型的哌啶基噻唑恶唑啉类杀菌剂，由拜耳作物科学公司于 2012 年开发。尽管其对植物病原卵菌如辣椒疫霉和致病疫霉具有良好的抑制活性已有充分的文献记载，但关于其抗真菌谱以及保护和治疗活性的信息有限。氟吡菌酰胺对卵菌纲和几种腐霉属真菌表现出很强的抑制活性，EC 值范围为 2.12×10 至 2.92μg/mL。它在抑制菌丝生长、孢子囊产生和胞囊孢子萌发方面比减少游动孢子释放对辣椒疫霉更为有效。此外，氟吡菌酰胺在温室条件下对辣椒疫霉感染具有保护和治疗活性，高效液相色谱（HPLC）分析证实了其具有系统转移能力。结果表明，氟吡菌酰胺对包括卵菌纲和几种腐霉属真菌在内的重要经济植物卵菌病原菌具有很强的抑制活性，并且在辣椒植物中有一定的转移活性。
