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65 岁以上入住重症监护病房的老年创伤患者的虚弱状况和 6 个月轨迹:1 级创伤中心的经验。

Frailty and 6-month trajectory of elderly trauma patients over the age of 65 years admitted to intensive care unit for severe trauma: experience of a level 1 trauma center.

机构信息

Surgical and Trauma Intensive Care Unit, Reims University Hospital, Reims, F-51100, France.

Anesthesiology, Critical Care and Perioperative Medicine, Reims University Hospital, Reims, F-51100, France.

出版信息

BMC Geriatr. 2024 Sep 14;24(1):759. doi: 10.1186/s12877-024-05350-1.


DOI:10.1186/s12877-024-05350-1
PMID:39277744
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11401312/
Abstract

BACKGROUND: The aging global population forecasts a significant rise in severe trauma cases among individuals aged 65 and above. Frailty emerges as a paramount predictor of post-traumatic outcomes, surpassing age and trauma severity indices. Despite this, scant attention is given to the trajectory of elderly patients post-intensive care unit (ICU) stay following severe trauma, justifying this study. The objective of this study was to analyze trajectories (frailty, place of residence) following a major trauma requiring an ICU stay. MATERIALS AND METHODS: An observational cohort study was conducted, leveraging data from a level 1 trauma center spanning 2018 to 2023. Inclusion criteria included elderly patients aged 65 and above admitted to the ICU for severe trauma. Data encompassed demographic profiles, trauma severity scores, clinical parameters, and frailty assessments sourced from the Traumabase database. RESULTS: Among 293 patients included 190 were non-frail, frailty was correlated with elevated mortality rates (114 (38.9%) at 6 months), heightened incidence of traumatic brain injuries, and notable declines in post-traumatic autonomy. Only 39.2% of patients had resumed residence at home six months post-injury, with a conspicuous trend towards institutionalization, particularly among frail individuals. CONCLUSION: This study highlights the role of frailty in determining the outcomes of elderly patients following severe trauma. Frailty is associated with higher mortality, increased rates of institutionalization, and a decline in functional status. These results highlight the importance of assessing frailty in the trajectory of severely injured patients over the age of 65 years-old.

摘要

背景:全球人口老龄化预计将导致 65 岁及以上人群中严重创伤病例显著增加。虚弱是创伤后结局的主要预测因素,超过了年龄和创伤严重程度指数。尽管如此,对于严重创伤后老年患者离开重症监护病房(ICU)后的轨迹,关注度仍然较低,这就是本研究的意义所在。本研究旨在分析需要 ICU 治疗的严重创伤后患者的轨迹(虚弱、居住地点)。

材料与方法:这是一项观察性队列研究,利用了一家 1 级创伤中心 2018 年至 2023 年的数据。纳入标准为年龄在 65 岁及以上、因严重创伤入住 ICU 的老年患者。数据包括人口统计学特征、创伤严重程度评分、临床参数和来自 Traumabase 数据库的虚弱评估。

结果:在 293 名患者中,190 名患者无虚弱,虚弱与 6 个月时的高死亡率(114 例(38.9%))相关,创伤性脑损伤的发生率更高,创伤后自主性显著下降。只有 39.2%的患者在受伤后 6 个月恢复家庭居住,机构化的趋势明显,尤其是在虚弱的患者中。

结论:本研究强调了虚弱在决定严重创伤后老年患者结局中的作用。虚弱与较高的死亡率、较高的机构化率和功能状态下降相关。这些结果突出了在 65 岁以上严重受伤患者的轨迹中评估虚弱的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ad4/11401312/5d1c392290b6/12877_2024_5350_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ad4/11401312/1f35fd90e511/12877_2024_5350_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ad4/11401312/434f50913a32/12877_2024_5350_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ad4/11401312/5d1c392290b6/12877_2024_5350_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ad4/11401312/1f35fd90e511/12877_2024_5350_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ad4/11401312/434f50913a32/12877_2024_5350_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ad4/11401312/5d1c392290b6/12877_2024_5350_Fig3_HTML.jpg

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本文引用的文献

[1]
The trajectory of very old critically ill patients.

Intensive Care Med. 2024-2

[2]
Does frailty impact failure-to-rescue in geriatric trauma patients?

J Trauma Acute Care Surg. 2024-5-1

[3]
Health care utilization and outcomes in older adults after Traumatic Brain Injury: A CENTER-TBI study.

Injury. 2022-8

[4]
The impact of frailty in major trauma in older patients.

Injury. 2020-7

[5]
Correlation between field triage criteria and the injury severity score of trauma patients in a French inclusive regional trauma system.

Scand J Trauma Resusc Emerg Med. 2019-8-5

[6]
Trajectory of functional outcome and health status after moderate-to-major trauma in Hong Kong: A prospective 5 year cohort study.

Injury. 2019-2-22

[7]
Management of frail older people with acute illness.

Intern Med J. 2019-1

[8]
Frailty and Prognostication in Geriatric Surgery and Trauma.

Clin Geriatr Med. 2018-10-3

[9]
Frailty score on admission predicts mortality and discharge disposition in elderly trauma patients over the age of 65 y.

J Surg Res. 2018-10

[10]
The Association of Frailty With Post-ICU Disability, Nursing Home Admission, and Mortality: A Longitudinal Study.

Chest. 2018-3-17

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