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高危低发疾病:大咯血。

High risk and low incidence diseases: Massive hemoptysis.

机构信息

Department of Emergency Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.

Department of Emergency Medicine, University of Kansas Medical Center, Kansas City, KS, USA.

出版信息

Am J Emerg Med. 2024 Nov;85:179-185. doi: 10.1016/j.ajem.2024.09.013. Epub 2024 Sep 10.

Abstract

BACKGROUND

Massive hemoptysis (MH) is a serious condition that carries with it a high rate of morbidity and mortality.

OBJECTIVE

This review highlights the pearls and pitfalls of massive hemoptysis, including presentation, diagnosis, and management in the emergency department (ED) based on current evidence.

DISCUSSION

MH is a rare but deadly condition. It is defined clinically as any bleeding from the tracheobronchial tree that compromises respiratory or circulatory function. The bronchial artery system is the primary source in the majority of cases of MH. The most common cause is tuberculosis worldwide, but bronchiectasis, bronchogenic carcinoma, and mycetoma are more common causes in the U.S. Patients with MH require rapid assessment and management, as decompensation can be rapid. Patients with altered mental status, inability to clear their sections, respiratory distress, or hemodynamic compromise require emergent airway intervention. The imaging modality of choice is computed tomography angiography with pulmonary arterial phase contrast. A reasonable order or sequence of management includes initial stabilization; assessment for the need for airway intervention; reversal of any coagulopathy; advanced imaging; and emergent consultation of pulmonary, cardiothoracic surgery, and interventional radiology. Ongoing resuscitation including blood products may be required in some patients with MH until definitive hemostasis is achieved.

CONCLUSIONS

An understanding of MH can assist emergency clinicians in diagnosing and managing this dangerous disease. Providing a prompt evaluation, obtaining intravenous access, pursuing advanced imaging, providing reversal of coagulopathy, supporting hemodynamics, and appropriate consultation are key interventions in MH.

摘要

背景

大咯血(MH)是一种严重的疾病,其发病率和死亡率都很高。

目的

本综述重点介绍了大咯血的要点和陷阱,包括根据现有证据在急诊科(ED)的表现、诊断和治疗。

讨论

MH 是一种罕见但致命的疾病。临床上定义为任何支气管树出血,导致呼吸或循环功能受损。在大多数情况下,支气管动脉系统是 MH 的主要来源。最常见的原因是全世界的结核病,但在支气管扩张症、支气管肺癌和真菌病在美国更常见。MH 患者需要快速评估和治疗,因为代偿可能很快发生。有精神状态改变、无法清除分泌物、呼吸困难或血流动力学不稳定的患者需要紧急气道干预。首选的成像方式是带肺动脉期对比的计算机断层血管造影。合理的管理顺序包括初始稳定;评估气道干预的必要性;纠正任何凝血障碍;进行高级影像学检查;并紧急咨询肺病、心胸外科和介入放射科。在一些 MH 患者中,可能需要持续复苏包括血液制品,直到达到明确的止血效果。

结论

对 MH 的了解可以帮助急诊临床医生诊断和治疗这种危险的疾病。快速评估、建立静脉通路、进行高级影像学检查、纠正凝血障碍、支持血流动力学和适当的咨询是 MH 的关键干预措施。

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