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使用含聚乙二醇的牙髓材料治疗后的过敏反应。

Anaphylaxis after Treatment with an Endodontic Material Containing Polyethylene Glycol.

作者信息

Alnæs Marie, Storaas Torgeir, Vindenes Hilde Kristin, Guttormsen Anne Berit, Björkman Lars

机构信息

Regional Center for Asthma, Allergy, and Hypersensitivity in Western Norway, Haukeland University Hospital, Bergen, Norway; Department of Clinical Medicine, University of Bergen, Bergen, Norway.

Regional Center for Asthma, Allergy, and Hypersensitivity in Western Norway, Haukeland University Hospital, Bergen, Norway.

出版信息

J Endod. 2024 Nov;50(11):1649-1654. doi: 10.1016/j.joen.2024.09.002. Epub 2024 Sep 13.

Abstract

Polyethylene glycol (PEG) is sometimes included in temporary endodontic filling materials to modify viscosity. PEG is considered a low hazard chemical, but parenteral PEG exposure is associated with a risk of anaphylaxis. We report 2 cases of anaphylaxis after treatment with an endodontic temporary filling material containing PEG. One patient survived after hospital treatment, but the second case was fatal. Extensive investigations were needed to find the culprit. Allergic reactions to PEG are increasingly reported and have significant implications for the patient. Precautionary measures are discussed.

摘要

聚乙二醇(PEG)有时会被添加到临时牙髓充填材料中以调节粘度。PEG被认为是一种低危害化学品,但经肠外途径接触PEG与过敏反应风险相关。我们报告了2例使用含PEG的牙髓临时充填材料治疗后发生过敏反应的病例。1例患者经住院治疗后存活,但第2例病例死亡。需要进行广泛调查以找出罪魁祸首。对PEG的过敏反应报告越来越多,对患者有重大影响。本文讨论了预防措施。

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