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结核病患者的管理和法医学在 COVID-19 大流行中的作用。

Management of tuberculosis patients and the role of forensic medicine in COVID-19 pandemic.

机构信息

Department of Microbiology, SRM Medical College Hospital and Research Centre, Kattangulathur, Chennai, 603203, Tamilnadu, India.

Department of Microbiology, Jaya College of Arts and Science, Tirunindravur, Chennai, 602024, Tamilnadu, India.

出版信息

Indian J Tuberc. 2024 Oct;71(4):481-487. doi: 10.1016/j.ijtb.2024.04.005. Epub 2024 Apr 13.

Abstract

Tuberculosis and Coronaviral disease-19 had a global impact in 2020 and still predominating, both infectious diseases similar to the lethal pandemics spread in one route, likely airborne transmission, the infected person could spread to healthy people. However, tuberculosis slightly varies from COVID-19. Though the primordial disease of the tuberculosis epidemic has had a vast impact on this society, besides the COVID-19 pandemic with other co-morbidities, conditions faced numerous complications. This review exemplified the impact of two lethal diseases in changing patient care, diagnostic issues, and forensic sciences roles. The diagnosis of tuberculosis with a massive concern due to standard testing methods, leading to inaccuracy, sensitivity, and prolonged time consumption. In addition, unavailability of testing kits, equipment failure, over-crowd in hospitals and fewer healthcare workers, a prolonged testing period, and finally, anxiety about COVID-19. Also, the contribution of forensic sciences in the autopsy of the exact cause of infectious diseases is crucial. Likewise, during this pandemic, there has been a drastic reduction in tuberculosis incidence in high-burden countries and a synergistic effect of both diseases. So, this review summarized the overall burden of tuberculosis management during COVID-19 and followed the guidelines of various nations' healthcare authorities to mitigate the consequences of tuberculosis diagnosis and prognosis during the pandemic.

摘要

结核病和 2019 年冠状病毒病(COVID-19)在 2020 年对全球产生了影响,并且仍然占据主导地位,这两种传染病都类似于通过单一途径传播的致命性大流行,可能通过空气传播,感染的人可能会将病毒传播给健康人。然而,结核病与 COVID-19 略有不同。尽管结核病疫情的原始疾病对这个社会产生了巨大影响,但除了 COVID-19 大流行带来的其他合并症外,还面临着许多并发症。本综述举例说明了这两种致命疾病在改变患者护理、诊断问题和法医学作用方面的影响。由于标准检测方法存在不准确、灵敏度低和耗时过长等问题,结核病的诊断受到了极大关注。此外,检测试剂盒的缺乏、设备故障、医院拥挤和医护人员较少、检测周期延长以及对 COVID-19 的担忧也导致了结核病诊断的困难。同样,法医学在确定传染病的确切病因方面的贡献也至关重要。同样,在大流行期间,高负担国家的结核病发病率急剧下降,这两种疾病也产生了协同作用。因此,本综述总结了 COVID-19 期间结核病管理的总体负担,并遵循了各国卫生当局的指导方针,以减轻大流行期间结核病诊断和预后的后果。

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