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[利福平治疗小鼠的肠上皮酶活性与超微结构]

[Enzyme activity and ultrastructure of the intestinal epithelium in mice treated with rifampicin].

作者信息

Cellesi C, Rossolini G M, Lusini P, Gerli R, Alessandrini C

出版信息

Boll Ist Sieroter Milan. 1985;64(2):150-4.

PMID:3927938
Abstract

Some enzymatic activities and the ultrastructure of the intestinal epithelium of mouse were valued after a treatment with rifampicin, per os, in different doses (25 mg/Kg and 50 mg/Kg), for 90 days. Neither alteration of maltase, lactase, leucine aminopeptidase (LAP), nor modification of the morphology of jejunal mucous membrane enterocytes and of their mitochondria were noticed in treated animals, as to controls.

摘要

经口给予小鼠不同剂量(25毫克/千克和50毫克/千克)的利福平处理90天后,对小鼠肠道上皮的一些酶活性和超微结构进行了评估。与对照组相比,在接受处理的动物中,未观察到麦芽糖酶、乳糖酶、亮氨酸氨肽酶(LAP)的改变,空肠黏膜肠上皮细胞及其线粒体的形态也未发生改变。

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