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选择性超声引导神经根阻滞可改善颈椎间盘疾病患者椎间盘切除术的疗效:一项随机、对照、单盲研究。

Selective ultrasound-guided nerve root block improves outcomes for discectomy in patients with cervical disc disease: a randomized, controlled, single-blinded study.

机构信息

Department of Anesthesia and Intensive Care, Faculty of Medicine, New Valley University, El-Kharga, Egypt -

Department of Anesthesia, Intensive Care and PAIN, University of Assiut, Assiut, Egypt -

出版信息

Minerva Anestesiol. 2024 Sep;90(9):748-758. doi: 10.23736/S0375-9393.24.17989-8.

Abstract

BACKGROUND

We hypothesized that ultrasound-guided selective nerve root block could play a role in the prediction of clinical outcomes in patients with multilevel cervical disease following selective anterior cervical discectomy and fusion.

METHODS

Patients were randomized to receive ultrasound-guided selected nerve root block as a diagnostic tool (study group) or not (control group), but both groups had surgery. Pain evaluation for arm and neck pain was recorded. The Visual Analog Scale (VAS) pain scores, Neck Disability Index, and MRI results were compared between groups. They were assessed every two weeks for three months, postoperatively. The percentage of patients who showed ≥ 50% reduction in their pain levels and a VAS rating of ≤2 was deemed an acceptable surgical outcome.

RESULTS

Patients in the study group had significantly lower VAS scores for pain intensity than control patients at nearly all periods. This baseline pain improved significantly in the study group. A more significant proportion of patients in the study group showed a ≥50% reduction in their pain scores from baseline at weeks four, eight, and 12, and this difference was significantly lower than in the control group (P<0.05). The study group improved significantly over baseline in Neck Disability Index scores compared to control patients. Patients were highly satisfied with no significant adverse events in the study group.

CONCLUSIONS

In patients with multilevel cervical disease, ultrasound-guided selective nerve root block is an excellent, safe, non-radiating, and reliable test to determine the appropriate level for operation.

摘要

背景

我们假设超声引导下选择性神经根阻滞可以在多节段颈椎疾病患者接受选择性前路颈椎间盘切除融合术后预测临床结果中发挥作用。

方法

将患者随机分为接受超声引导下选择性神经根阻滞作为诊断工具的组(研究组)和不接受组(对照组),但两组均进行手术。记录手臂和颈部疼痛的疼痛评估。比较两组之间的视觉模拟量表(VAS)疼痛评分、颈椎残疾指数和 MRI 结果。术后每两周评估一次,共三个月。

结果

研究组患者在几乎所有时间段的疼痛强度 VAS 评分均显著低于对照组患者。该基线疼痛在研究组中显著改善。研究组中更多比例的患者在第 4、8 和 12 周时的疼痛评分从基线下降≥50%,这一差异明显低于对照组(P<0.05)。与对照组相比,研究组的颈椎残疾指数评分在基线水平上显著提高。研究组患者对无明显不良事件的满意度较高。

结论

在多节段颈椎疾病患者中,超声引导下选择性神经根阻滞是一种优秀、安全、非辐射和可靠的测试方法,可确定手术的合适水平。

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