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一名 transgender 女性中的偶发性睾丸生殖细胞肿瘤:病例报告。 (注:“transgender woman”直译为“跨性别女性”,指生理性别与心理性别不一致的女性群体)

Incidental testicular germ cell tumor in a transgender woman: A case report.

作者信息

Aslanian R Evey, Roblee Cole, Smith David C, Mehra Rohit, Kuzon William M

机构信息

Section of Plastic Surgery, Department of Surgery, University of Michigan, 1500 E Medical Center Dr, Ann Arbor, MI, USA.

University of Michigan Medical School, 1301 Catherine St, Ann Arbor, MI, USA.

出版信息

Urol Case Rep. 2024 Aug 3;56:102817. doi: 10.1016/j.eucr.2024.102817. eCollection 2024 Sep.

DOI:10.1016/j.eucr.2024.102817
PMID:39280132
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11402054/
Abstract

Testicular cancer found incidentally during gender-affirming orchiectomy is infrequently reported in the literature. This report details a 27-year-old transgender woman whose testicular cancer was discovered incidentally upon routine histopathologic examination of the orchiectomy specimen. The patient did not present with any clinical signs of malignancy. There was no evidence of metastases after further workup and the patient was able to resume hormone therapy after surgery. Transgender individuals must be screened according to their natal anatomy and even in absence of clinical signs excised tissue should be examined for possible malignancy.

摘要

在性别确认睾丸切除术中偶然发现的睾丸癌在文献中鲜有报道。本报告详细介绍了一名27岁的跨性别女性,其睾丸癌是在对睾丸切除标本进行常规组织病理学检查时偶然发现的。该患者没有任何恶性肿瘤的临床症状。进一步检查后没有转移的迹象,患者术后能够恢复激素治疗。跨性别个体必须根据其出生时的解剖结构进行筛查,即使没有临床症状,切除的组织也应检查是否可能存在恶性肿瘤。

相似文献

1
Incidental testicular germ cell tumor in a transgender woman: A case report.一名 transgender 女性中的偶发性睾丸生殖细胞肿瘤:病例报告。 (注:“transgender woman”直译为“跨性别女性”,指生理性别与心理性别不一致的女性群体)
Urol Case Rep. 2024 Aug 3;56:102817. doi: 10.1016/j.eucr.2024.102817. eCollection 2024 Sep.
2
Histological study on the influence of puberty suppression and hormonal treatment on developing germ cells in transgender women.青春期抑制和激素治疗对跨性别女性生殖细胞发育影响的组织学研究。
Hum Reprod. 2022 Jan 28;37(2):297-308. doi: 10.1093/humrep/deab240.
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本文引用的文献

1
National Estimates of Gender-Affirming Surgery in the US.美国的性别肯定手术的国家估计数。
JAMA Netw Open. 2023 Aug 1;6(8):e2330348. doi: 10.1001/jamanetworkopen.2023.30348.
2
Cancer screening and management in the transgender population: Review of literature and special considerations for gender affirmation surgery.transgender人群的癌症筛查与管理:文献综述及性别肯定手术的特殊考量
World J Clin Oncol. 2023 Jul 24;14(7):265-284. doi: 10.5306/wjco.v14.i7.265.
3
Standards of Care for the Health of Transgender and Gender Diverse People, Version 8.
《跨性别和性别多样化人群健康照护标准》第8版
Int J Transgend Health. 2022 Sep 6;23(Suppl 1):S1-S259. doi: 10.1080/26895269.2022.2100644. eCollection 2022.
4
Clinicopathologic features and proposed grossing protocol of orchiectomy specimens performed for gender affirmation surgery.用于性别肯定手术的睾丸切除术标本的临床病理特征和提出的大体检查方案。
Hum Pathol. 2022 Sep;127:21-27. doi: 10.1016/j.humpath.2022.05.017. Epub 2022 Jun 2.
5
Incidence of Testicular Cancer in Transfeminine Patients following Vaginoplasty with Orchidectomy.睾丸切除术后阴道成形术的跨性别女性患者睾丸癌发病率。
Plast Reconstr Surg Glob Open. 2022 Apr 18;10(4):e4051. doi: 10.1097/GOX.0000000000004051. eCollection 2022 Apr.
6
Testicular mixed germ cell tumor in a transgender woman.一名 transgender 女性的睾丸混合性生殖细胞肿瘤。
Urol Case Rep. 2021 Oct 1;40:101861. doi: 10.1016/j.eucr.2021.101861. eCollection 2022 Jan.
7
Incidence of testicular cancer in trans women using gender-affirming hormonal treatment: a nationwide cohort study.使用性别肯定激素治疗的跨性别女性的睾丸癌发病率:一项全国性队列研究。
BJU Int. 2022 Apr;129(4):491-497. doi: 10.1111/bju.15575. Epub 2021 Aug 30.
8
Histologic Findings in Surgical Pathology Specimens From Individuals Taking Feminizing Hormone Therapy for the Purpose of Gender Transition.接受激素疗法以进行性别转换的个体的外科病理学标本的组织学发现。
Arch Pathol Lab Med. 2022 Jan 2;146(2):252-261. doi: 10.5858/arpa.2020-0704-RA.
9
Incidence of Cancer and Premalignant Lesions in Surgical Specimens of Transgender Patients.跨性别患者手术标本中的癌症和癌前病变发生率。
Plast Reconstr Surg. 2021 Jan 1;147(1):194-198. doi: 10.1097/PRS.0000000000007452.
10
Unmasked Testicular Seminoma During Use of Hormonal Transgender Woman Therapy: A Hidden hCG-Secreting Tumor.激素治疗跨性别女性期间发现的睾丸精原细胞瘤:一种隐匿的分泌人绒毛膜促性腺激素的肿瘤。
J Endocr Soc. 2020 Jun 18;4(7):bvaa074. doi: 10.1210/jendso/bvaa074. eCollection 2020 Jul 1.