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一名口腔内有肿物的胎儿:罕见的巨大口腔未成熟畸胎瘤病例。

A fetus with a mass in the oral cavity: A rare case of large oral immature teratoma.

作者信息

Anjum Saba, Siddiqui Humza Faisal, Arshad Sidra

机构信息

Histopathology Section, Department of Pathology, Ziauddin University Hospital, Karachi, Pakistan.

Jinnah Sindh Medical University, Karachi, Pakistan.

出版信息

SAGE Open Med Case Rep. 2024 Sep 14;12:2050313X241275027. doi: 10.1177/2050313X241275027. eCollection 2024.

DOI:10.1177/2050313X241275027
PMID:39280334
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11402092/
Abstract

Oral teratoma is a congenital neoplastic lesion with an incidence of 2%-9% of all teratomas. It comprises variable amounts of all three germ cell layers. The lesion is graded on histology depending upon the presence of immature components. The most common sites of presentation are the sacrococcygeal area and head and neck with slight female predominance. Our report is based on a case that was received for histopathological evaluation. It consisted of a 20-week fetus with a huge mass protruding from oral orifice measuring 10.8 × 6.7 cm. Histological examination of the tumor revealed immature teratoma-oropharynx.

摘要

口腔畸胎瘤是一种先天性肿瘤性病变,在所有畸胎瘤中发病率为2% - 9%。它由所有三个胚层的不同数量组织构成。根据组织学上未成熟成分的存在情况对病变进行分级。最常见的发病部位是骶尾部和头颈部,女性略占优势。我们的报告基于一例接受组织病理学评估的病例。该病例为一名20周大的胎儿,口腔有一巨大肿物突出,大小为10.8×6.7厘米。肿瘤的组织学检查显示为口咽部未成熟畸胎瘤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1298/11402092/c89d2b41ace8/10.1177_2050313X241275027-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1298/11402092/b462ebdc19b5/10.1177_2050313X241275027-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1298/11402092/4ef238af24b2/10.1177_2050313X241275027-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1298/11402092/e5e2063c5e6e/10.1177_2050313X241275027-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1298/11402092/c89d2b41ace8/10.1177_2050313X241275027-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1298/11402092/b462ebdc19b5/10.1177_2050313X241275027-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1298/11402092/4ef238af24b2/10.1177_2050313X241275027-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1298/11402092/e5e2063c5e6e/10.1177_2050313X241275027-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1298/11402092/c89d2b41ace8/10.1177_2050313X241275027-fig4.jpg

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本文引用的文献

1
Prenatal Diagnosis of Oral Teratoma by Ultrasound.超声产前诊断口腔畸胎瘤
J Med Ultrasound. 2022 Oct 4;32(1):76-78. doi: 10.4103/jmu.jmu_47_22. eCollection 2024 Jan-Mar.
2
Mature Cystic Oral Teratoma in a Neonate- A Case Report.新生儿成熟囊性口腔畸胎瘤——病例报告
Indian J Otolaryngol Head Neck Surg. 2024 Apr;76(2):1994-1997. doi: 10.1007/s12070-023-04336-6. Epub 2023 Nov 25.
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Immature Teratoma: Diagnosis and Management-A Review of the Literature.未成熟畸胎瘤:诊断与管理——文献综述
Diagnostics (Basel). 2023 Apr 23;13(9):1516. doi: 10.3390/diagnostics13091516.
4
Immature nasopharyngeal teratoma with prenatal diagnosis: Case report and review of the literature.产前诊断未成熟型鼻咽部畸胎瘤 1 例并文献复习
Rev Colomb Obstet Ginecol. 2023 Mar 30;74(1):68-86. doi: 10.18597/rcog.3906.
5
Teratoma of the Tongue in a Fetus: A Case Report and Review of the Literature.胎儿舌部畸胎瘤:一例报告并文献复习
Pediatr Dev Pathol. 2023 Jan-Feb;26(1):86-90. doi: 10.1177/10935266221132353. Epub 2022 Nov 28.
6
A fetus with a mass in the oral cavity: a rare case of oral immature teratoma.一名口腔内有肿物的胎儿:口腔未成熟畸胎瘤的罕见病例。
Int J Clin Exp Pathol. 2017 Jul 1;10(7):7890-7892. eCollection 2017.
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Teratoma of the neonatal head and neck: A 41-year experience.新生儿头颈部畸胎瘤:41年的经验
Int J Pediatr Otorhinolaryngol. 2017 Jun;97:66-71. doi: 10.1016/j.ijporl.2017.02.011. Epub 2017 Feb 14.
8
Successful in utero treatment of an oral teratoma via operative fetoscopy: case report and review of the literature.经手术胎儿镜成功治疗宫内口腔畸胎瘤:病例报告及文献复习。
Am J Obstet Gynecol. 2012 Jul;207(1):e12-5. doi: 10.1016/j.ajog.2012.04.008. Epub 2012 Apr 5.
9
Cervical and oral teratoma in the fetus: a systematic review of etiology, pathology, diagnosis, treatment and prognosis.胎儿宫颈和口腔的畸胎瘤:病因、病理学、诊断、治疗和预后的系统回顾。
Arch Gynecol Obstet. 2010 Oct;282(4):355-61. doi: 10.1007/s00404-010-1500-7. Epub 2010 May 15.
10
Mushroom-shaped teratoma of the soft palate in a neonate: case report.新生儿软腭蘑菇状畸胎瘤:病例报告
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