Mehros Wala, Al-Jifree Hatim, Saber Arwa, Saber Anfal, Makki Reham, Fallatah Batoul, Hakami Alqassem Y, Khan Muhammad A
Obstetrics and Gynaecology, King Saud Bin Abdulaziz University for Health Sciences College of Medicine, Jeddah, SAU.
Oncology, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Jeddah, SAU.
Cureus. 2024 Aug 14;16(8):e66841. doi: 10.7759/cureus.66841. eCollection 2024 Aug.
Venous thromboembolism, which includes deep-vein thrombosis and pulmonary embolism, is the third most common cardiovascular disease after myocardial infarction and stroke. This study aimed to determine the effect of Doppler ultrasound on the prophylaxis and prevention of postoperative venous thromboembolism in gynecological oncology.
This is a retrospective cohort study of procedures performed at King Abdulaziz Medical City in Jeddah, Saudi Arabia, between 2016 and 2021. The study included all patients diagnosed with gynecological cancers who underwent major cancer resection. A total of 295 eligible patients were enrolled and divided into two groups: the first group consisted of 104 patients who were screened for deep vein thrombosis using lower limb Doppler ultrasound prior to their gynecologic oncology surgery, while the second group included 190 patients who were not screened.
The prevalence of pulmonary embolism and/or deep vein thrombosis was found to be eight out of 104 patients (7.7%) in the group screened for deep-vein thrombosis using lower limb Doppler ultrasound prior to their gynecologic oncology surgery. In the group that was not screened, one out of 190 patients (0.5%) developed deep vein thrombosis. The prevalence of postoperative pulmonary embolism and/or deep-vein thrombosis was reported in four out of 104 screened patients (3.8%) and in three out of 190 patients (1.6%) in the unscreened group.
This study concluded that Doppler screening did not change the incidence of pulmonary embolism and/or deep-vein thrombosis postoperatively, but it may be helpful in detecting these conditions preoperatively. Therefore, Doppler screening for deep-vein thrombosis before surgical procedures in gynecological oncology could be considered after clinical assessment of the patient. To improve the study and address its limitations, a larger sample size would help to further investigate and identify relevant factors and determine their significance.
静脉血栓栓塞症，包括深静脉血栓形成和肺栓塞，是仅次于心肌梗死和中风的第三大常见心血管疾病。本研究旨在确定多普勒超声对妇科肿瘤术后静脉血栓栓塞症的预防作用。
这是一项对2016年至2021年期间在沙特阿拉伯吉达阿卜杜勒阿齐兹国王医疗城进行的手术的回顾性队列研究。该研究纳入了所有被诊断为妇科癌症并接受重大癌症切除术的患者。共有295名符合条件的患者入组并分为两组：第一组由104名在妇科肿瘤手术前使用下肢多普勒超声筛查深静脉血栓形成的患者组成，而第二组包括190名未接受筛查的患者。
在妇科肿瘤手术前使用下肢多普勒超声筛查深静脉血栓形成的组中，104名患者中有8名（7.7%）发生了肺栓塞和/或深静脉血栓形成。在未接受筛查的组中，190名患者中有1名（0.5%）发生了深静脉血栓形成。在接受筛查的104名患者中有4名（3.8%）报告了术后肺栓塞和/或深静脉血栓形成的发生率，在未接受筛查组中的190名患者中有3名（1.6%）报告了该发生率。
本研究得出结论，多普勒筛查并未改变术后肺栓塞和/或深静脉血栓形成的发生率，但可能有助于在术前检测出这些情况。因此，在对患者进行临床评估后，可以考虑在妇科肿瘤手术前对深静脉血栓形成进行多普勒筛查。为了改进研究并解决其局限性，更大的样本量将有助于进一步调查和识别相关因素并确定其重要性。
