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男性吊带术与人工尿道括约肌治疗前列腺切除术后尿失禁的系统评价及Meta分析

Male sling versus artificial urinary sphincter for the treatment of incontinence after prostate surgery: a systematic review with meta-analysis.

作者信息

Chen Hai-Chao, Hu Peng-Cheng, Yao Jia-Tao, Ye Shi-Jie, Ma Qi

机构信息

Department of Urology, The First Affiliated Hospital of Ningbo University, Ningbo, China.

Health Science Center, Ningbo University, Ningbo, China.

出版信息

Transl Androl Urol. 2024 Aug 31;13(8):1416-1424. doi: 10.21037/tau-24-107. Epub 2024 Aug 23.

Abstract

BACKGROUND

Urinary incontinence following prostate treatment (IPT) represents a significant complication that detrimentally impacts the quality of life for patients who have undergone prostate surgery. Presently, there is a scarcity of evidence regarding the preferred surgical techniques for IPT. We conducted a meta-analysis to compare the outcomes of the male sling and artificial urinary sphincter (AUS) in the treatment of IPT.

METHODS

Data were extracted through electronic literature searches on PubMed, Web of Science, and Embase databases until September 2023. Eligible studies included patients who underwent AUS or male sling procedures for IPT and had a follow-up duration exceeding 12 months. The primary end point was the success rate, with the secondary outcome focusing on complication rates. A fixed-effects or random-effects models were used to calculate the pooled estimate and its 95% confidence interval (CI). The publication bias was assessed using funnel plots and Egger's regression test.

RESULTS

The meta-analysis included nine studies, involving a total of 1,350 participants. No statistically significant difference in success rates was found between AUS and male sling [odds ratio (OR): 0.96, 95% CI: 0.91-1.01]. In terms of the complication rate, there was no significant disparity between the two procedures (OR: 0.87, 95% CI: 0.86-1.12).

CONCLUSIONS

The findings from this study indicated that male sling surgery yielded success and complication rates comparable to those of AUS. This suggests that male sling could serve as a viable alternative surgical option in the treatment of IPT.

摘要

背景

前列腺治疗后尿失禁(IPT)是一种严重并发症,对接受前列腺手术的患者生活质量产生不利影响。目前,关于IPT首选手术技术的证据匮乏。我们进行了一项荟萃分析,比较男性吊带术和人工尿道括约肌(AUS)治疗IPT的效果。

方法

通过在PubMed、科学网和Embase数据库进行电子文献检索,直至2023年9月提取数据。符合条件的研究包括接受AUS或男性吊带术治疗IPT且随访时间超过12个月的患者。主要终点是成功率,次要结果集中在并发症发生率。采用固定效应或随机效应模型计算合并估计值及其95%置信区间(CI)。使用漏斗图和Egger回归检验评估发表偏倚。

结果

荟萃分析纳入9项研究,共1350名参与者。AUS和男性吊带术的成功率无统计学显著差异[优势比(OR):0.96,95%CI:0.91 - 1.01]。在并发症发生率方面,两种手术之间无显著差异(OR:0.87,95%CI:0.86 - 1.12)。

结论

本研究结果表明,男性吊带术的成功率和并发症发生率与AUS相当。这表明男性吊带术可作为IPT治疗中一种可行的替代手术选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de1a/11399032/9ab93a30da64/tau-13-08-1416-f1.jpg

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