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一例采用球囊闭塞联合治疗方法(b-MWA + b-TAE)治疗肉瘤复发的病例报告。

A case report of sarcoma recurrence treated with a balloon-occluded combined approach (b-MWA + b-TAE).

作者信息

Punzi Ernesto, Porcaro Piercarmine, Flora Emanuele, Izzo Andrea, Amodeo Enrico Maria, Lombardi Giulio

机构信息

Department of Radiology, "St. Giuseppe Moscati" Hospital of National Relevance and High Specialty, Avellino, Italy.

Department of Precision Medicine, University of Campania "L. Vanvitelli", Caserta, Italy.

出版信息

Radiol Case Rep. 2024 Aug 27;19(11):5294-5298. doi: 10.1016/j.radcr.2024.07.180. eCollection 2024 Nov.

DOI:10.1016/j.radcr.2024.07.180
PMID:39280746
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11399786/
Abstract

Sarcomas present challenges in management due to their aggressive nature. Interventional radiology, utilizing ablation and embolization, offer promising alternatives for recurrent cases. In recent years, combined techniques (ablation + embolization) and the use of balloon-microcatheter have been introduced to enhance the necrotic effect in HCC treatment. This paper presents the case of a 47-year-old female with recurrent abdominal sarcoma treated with balloon-occluded microwave ablation (b-MWA) and balloon-occluded transarterial embolization (b-TAE). Post-treatment imaging revealed a significant reduction in lesion size and absence of pathological contrast enhancement. This study highlights the potential of balloon-catheter-assisted combined therapies (b-MWA + b-TAE) in managing sarcomas, expanding the applicability of interventional radiology for inoperable cases that are too large for ablative therapy alone or requiring multiple antennas. Further research is warranted to refine protocols and enhance patient outcomes in sarcoma management.

摘要

肉瘤因其侵袭性本质,在治疗管理方面存在挑战。介入放射学通过消融和栓塞技术,为复发病例提供了有前景的替代方案。近年来,联合技术(消融+栓塞)以及球囊微导管的使用已被引入,以增强肝癌治疗中的坏死效果。本文介绍了一例47岁复发性腹部肉瘤女性患者,接受球囊闭塞微波消融(b-MWA)和球囊闭塞经动脉栓塞(b-TAE)治疗的病例。治疗后的影像学检查显示病变大小显著减小,且无病理性对比增强。本研究强调了球囊导管辅助联合治疗(b-MWA+b-TAE)在肉瘤治疗中的潜力,扩大了介入放射学在因太大而无法单独进行消融治疗或需要多根天线的不可手术病例中的适用性。有必要进行进一步研究以完善方案并改善肉瘤治疗中的患者预后。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b0a/11399786/364bad3de79c/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b0a/11399786/f6732fa81b86/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b0a/11399786/4b4b174e60be/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b0a/11399786/b330a4576c67/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b0a/11399786/b3f611680fab/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b0a/11399786/364bad3de79c/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b0a/11399786/f6732fa81b86/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b0a/11399786/4b4b174e60be/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b0a/11399786/b330a4576c67/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b0a/11399786/b3f611680fab/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b0a/11399786/364bad3de79c/gr5.jpg

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本文引用的文献

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Cancers (Basel). 2023 Oct 20;15(20):5076. doi: 10.3390/cancers15205076.
2
Transarterial Embolization and Percutaneous Ablation of Primary and Metastatic Soft Tissue Tumors.经动脉栓塞及经皮消融治疗原发性和转移性软组织肿瘤
Life (Basel). 2023 Jun 30;13(7):1485. doi: 10.3390/life13071485.
3
Percutaneous Thermal Segmentectomy: Proof of Concept.
经皮热段切除术:概念验证。
Cardiovasc Intervent Radiol. 2022 May;45(5):665-676. doi: 10.1007/s00270-022-03117-y. Epub 2022 Mar 30.
4
Balloon-Occluded MWA (b-MWA) Followed by Balloon-Occluded TACE (b-TACE): Technical Note on a New Combined Single-Step Therapy for Single Large HCC.球囊阻断性微波消融(b-MWA)序贯球囊阻断性肝动脉化疗栓塞(b-TACE):一种治疗单发大肝癌的新型联合单步治疗新技术的技术说明。
Cardiovasc Intervent Radiol. 2020 Nov;43(11):1702-1707. doi: 10.1007/s00270-020-02583-6. Epub 2020 Jul 16.
5
Imaging of soft tissue sarcomas.软组织肉瘤的影像学检查
Chin Clin Oncol. 2018 Aug;7(4):35. doi: 10.21037/cco.2018.07.06.
6
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