Chai Melinda, Vining Amanda, Koveleskie Joseph, Sumrall William, Nossaman Bobby D
The University of Queensland Medical School, Ochsner Clinical School, New Orleans, LA.
Department of Anesthesiology and Perioperative Medicine, Ochsner Clinic Foundation, New Orleans, LA.
Ochsner J. 2024 Fall;24(3):192-197. doi: 10.31486/toj.24.0041.
Obesity, defined as a body mass index ≥30 kg/m, is epidemic in the United States and is associated with increased risks of adverse events. Studies have examined the role of maternal obesity on the incidence of instrumental vaginal delivery, but the results are divided. However, these analyses used frequentist tests that risk false discovery. The purpose of this retrospective study was to quantify the association of maternal obesity to the need for instrumental delivery with measures of effect size. Measures of effect size allow assessment of the impact of clinical risk factors on outcomes of interest. All parturients aged ≥18 years in active labor at our facility from January 2018 to May 2019 were entered into this study. Patient demographics, previously reported comorbidities, and obstetric parameters were collected and analyzed to determine the clinical impact of maternal obesity on the incidence of instrumental delivery. One effect size measure, risk differences, was used to quantify the clinical effect of maternal obesity on the need for instrumental delivery. A generalized linear model was used to standardize the measures of effect size of previously reported comorbidities, including maternal obesity, and to determine their association with the need for instrumental delivery. The incidences of chronic and gestational hypertension, preeclampsia, chronic diabetes, and reactive airway disease were higher in parturients with maternal obesity. Risk differences due to maternal obesity were observed in parturients presenting with shoulder dystocia but not in those who underwent oxytocin induction or in nulliparous parturients. Following regression analysis, maternal obesity did not clinically impact the need for instrumental delivery. These findings suggest that maternal obesity did not have a clinical impact on the need for instrumental delivery.
肥胖定义为体重指数≥30kg/m²,在美国呈流行趋势,且与不良事件风险增加相关。已有研究探讨了孕妇肥胖对器械助产分娩发生率的影响,但结果存在分歧。然而,这些分析使用的频率检验存在错误发现的风险。这项回顾性研究的目的是通过效应量测量来量化孕妇肥胖与器械助产分娩需求之间的关联。效应量测量有助于评估临床风险因素对感兴趣结局的影响。2018年1月至2019年5月在我们机构中所有年龄≥18岁且处于活跃分娩期的产妇均纳入本研究。收集并分析患者人口统计学数据、先前报告的合并症以及产科参数,以确定孕妇肥胖对器械助产分娩发生率的临床影响。一种效应量测量方法,即风险差异,用于量化孕妇肥胖对器械助产分娩需求的临床影响。使用广义线性模型对先前报告的合并症(包括孕妇肥胖)的效应量测量进行标准化,并确定它们与器械助产分娩需求的关联。孕妇肥胖的产妇中慢性高血压、妊娠期高血压、先兆子痫、慢性糖尿病和反应性气道疾病的发生率较高。在出现肩难产的产妇中观察到孕妇肥胖导致的风险差异,但在接受催产素引产的产妇或初产妇中未观察到。经过回归分析,孕妇肥胖在临床上并未影响器械助产分娩的需求。这些发现表明,孕妇肥胖对器械助产分娩的需求没有临床影响。