Sattar Kamran, Karim Syed Irfan, Akram Ashfaq, Alrashed Fahad Abdulaziz
Kamran Sattar, MBBS, MMEd, PhD Department of Medical Education, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Syed Irfan Karim, MBBS, FRCGP Department of Family and Community Medicine, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Pak J Med Sci. 2024 Sep;40(8):1651-1657. doi: 10.12669/pjms.40.8.9003.
This study sought to quantify the link between low density lipoprotein (LDL) and cholesterol, glycemic control as measured by Hemoglobin A1c (HbA1c) level, and the impact of weight changes on subsequent risk of chronic heart disease in type-2 diabetes mellitus patients.
This study was conducted at Primary Care Clinics from April to September 2023. The data were retrieved from the e-SiHi (a patient care management system). Appropriate parametric tests and non-parametric analysis were applied following the normality of the data.
In diabetes mellitus (DM) patients, the Pearson correlation between the cholesterol and LDL relationship was found to be strongly positive and statistically significant (r = .877, p <.001). HbA1c and cholesterol were moderately positive and statistically significant (r =.330, =.003). Pearson correlation between DM and weight was found to be positive and statistically significant (r =.212, =.05). Chi-square analysis showed an association of DM with Hypertension, and this association was also significant; X2 (1, n = 83; 11.877; <.001).
Diabetes mellitus regardless of gender, has a strong association with hypertension and weight gain. In DM patients, cholesterol and HbA1c are positively correlated. There is a strong need that primary care physicians should persistently advise for lifestyle changes in all their consultations with DM patients.
本研究旨在量化低密度脂蛋白（LDL）与胆固醇之间的联系、通过糖化血红蛋白（HbA1c）水平衡量的血糖控制情况，以及体重变化对2型糖尿病患者后续慢性心脏病风险的影响。
本研究于2023年4月至9月在基层医疗诊所进行。数据从电子SiHi（一个患者护理管理系统）中检索。根据数据的正态性应用适当的参数检验和非参数分析。
在糖尿病（DM）患者中，发现胆固醇与LDL之间的Pearson相关性呈强正相关且具有统计学意义（r = 0.877，p < 0.001）。HbA1c与胆固醇呈中度正相关且具有统计学意义（r = 0.330，p = 0.003）。发现DM与体重之间的Pearson相关性呈正相关且具有统计学意义（r = 0.212，p = 0.05）。卡方分析显示DM与高血压之间存在关联，且这种关联也具有显著性；X2（1，n = 83；11.877；p < 0.001）。
无论性别，糖尿病都与高血压和体重增加密切相关。在DM患者中，胆固醇和HbA1c呈正相关。基层医疗医生在与DM患者的所有会诊中都应持续建议其改变生活方式，这一点非常必要。
