Tareen Saffa, Mooghal Mehwish, Shaikh Kulsoom, Zeeshan Sana
Saffa Tareen, MBBS Resident Surgery, Department of Surgery, The Aga Khan University, Karachi, Pakistan.
Mehwish Mooghal, FCPS Fellow Breast Surgery, Department of Surgery, The Aga Khan University, Karachi, Pakistan.
Pak J Med Sci. 2024 Sep;40(8):1847-1852. doi: 10.12669/pjms.40.8.9132.
This literature review explores breast cancer screening practices among transgender individuals globally, emphasizing the overlooked population in Pakistan. With an overview of intersex and transgender terminology, the study delves into screening guidelines for transfeminine and transmasculine patients, considering hormone therapy and surgery. Worldwide statistics on transgender and intersex populations are provided, highlighting the unique challenges they face, particularly in Pakistan, where societal discrimination and healthcare barriers persist. Databases searched included PubMed, Scopus, and Google Scholar from the Year 2000 till todate.The review synthesizes breast cancer screening recommendations in transgender population from ACR, WPATH, UCSF, and the Canadian Cancer Society, revealing variations in guidelines. It concludes with a call for tailored screening protocols for Pakistan's transgender community and recommends a comprehensive study due to the absence of data in Southeast Asia. The unstructured abstract underscores the need for nuanced, personalized screening strategies and emphasizes the critical gap in knowledge specific to breast cancer in this marginalized population.
这篇文献综述探讨了全球跨性别者中的乳腺癌筛查实践,着重关注了巴基斯坦被忽视的这一人群。在对双性人和跨性别术语进行概述后,该研究深入探讨了针对跨女性和跨男性患者的筛查指南,同时考虑了激素疗法和手术。文中提供了全球跨性别者和双性人人群的统计数据,突出了他们所面临的独特挑战,尤其是在巴基斯坦,社会歧视和医疗障碍依然存在。检索的数据库包括2000年至今的PubMed、Scopus和谷歌学术。该综述综合了美国放射学会(ACR)、世界跨性别健康专业协会(WPATH)、加州大学旧金山分校(UCSF)和加拿大癌症协会针对跨性别者人群的乳腺癌筛查建议,揭示了指南中的差异。文章最后呼吁为巴基斯坦的跨性别群体制定量身定制的筛查方案,并鉴于东南亚缺乏相关数据建议开展一项全面研究。非结构化摘要强调了需要有细致入微、个性化的筛查策略,并突出了这一边缘化人群中关于乳腺癌的特定知识的关键空白。