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跨性别者的乳腺癌风险与筛查:呼吁提供包容的护理。

Breast Cancer Risk and Screening in Transgender Persons: A Call for Inclusive Care.

机构信息

Division of Surgical Oncology, Department of Surgery, Medical College of Wisconsin, Milwaukee, WI, USA.

Department of Surgery, Duke University Medical Center, Durham, NC, USA.

出版信息

Ann Surg Oncol. 2022 Apr;29(4):2176-2180. doi: 10.1245/s10434-021-10217-5. Epub 2021 Jun 7.

DOI:10.1245/s10434-021-10217-5
PMID:34097159
Abstract

The Society of Surgical Oncology is committed to reducing health disparities adversely affecting sexual and gender minorities. Transgender persons represent a socially disadvantaged group who frequently experience discrimination and receive disparate care, resulting in suboptimal cancer outcomes. The rate of breast cancer development in transgender individuals differs from rates observed in their cisgender counterparts, however there is little evidence to quantify these differences and guide evidence-based screening and prevention. There is no consensus for breast cancer screening guidelines in transgender patients. In this review, we discuss barriers to equitable breast cancer care, risk factors for breast cancer development, and existing data to support breast cancer screening in transgender men and women.

摘要

外科肿瘤学会致力于减少对性少数群体和性别少数群体造成不利影响的健康差距。跨性别者是一个社会弱势群体,他们经常遭受歧视,并接受不同的护理,导致癌症治疗效果不佳。跨性别者的乳腺癌发病率与顺性别者的发病率不同,但几乎没有证据可以量化这些差异,并指导基于证据的筛查和预防。跨性别患者的乳腺癌筛查指南尚无共识。在这篇综述中,我们讨论了公平获得乳腺癌护理的障碍、乳腺癌发病的危险因素以及支持跨性别男性和女性进行乳腺癌筛查的现有数据。

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本文引用的文献

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Cancer screening rates among transgender adults: Cross-sectional analysis of primary care data.跨性别成年人的癌症筛查率:初级保健数据的横断面分析。
Can Fam Physician. 2019 Jan;65(1):e30-e37.
乳腺癌和卵巢癌风险的当前见解:一项当代综述。
Minerva Surg. 2025 Aug;80(4):334-353. doi: 10.23736/S2724-5691.25.10651-5.
4
Contemporary Considerations for Breast Cancer Risk and Screening in Transgender, Nonbinary, and Gender-Diverse Populations.变性者、非二元性别者及性别多样化人群乳腺癌风险与筛查的当代考量
Curr Breast Cancer Rep. 2025;17. doi: 10.1007/s12609-025-00573-6. Epub 2025 Feb 13.
5
Underinvested, Under-Referred, and Underserved: Applying a Gender Equity Continuum Framework in Cancer Control Continuum Programs and Policies to Expand to Transgender and Nonbinary Populations.投资不足、转诊不足和服务不足:在癌症控制连续项目和政策中应用性别平等连续统一体框架,以扩大至跨性别和非二元性别群体。
JCO Oncol Adv. 2025 May 7;2(1):e2400023. doi: 10.1200/OA.24.00023. eCollection 2025.
6
Implications of hormonal carcinogenesis for transgender and gender-diverse people undergoing gender-affirming hormone therapy: an up-to-date review.激素致癌作用对接受性别确认激素治疗的跨性别者和性别多样化人群的影响:最新综述
BMJ Oncol. 2024 May 31;3(1):e000330. doi: 10.1136/bmjonc-2024-000330. eCollection 2024.
7
Construction, validation, and visualization of a web-based nomogram to predict survival in male breast cancer patients with second primary prostate cancer.用于预测男性乳腺癌合并第二原发性前列腺癌患者生存率的基于网络的列线图的构建、验证及可视化。
Gland Surg. 2024 Nov 30;13(11):2023-2042. doi: 10.21037/gs-24-287. Epub 2024 Nov 26.
8
UK recommendations for the management of transgender and gender-diverse patients with inherited cancer risks.英国对患有遗传性癌症风险的跨性别和性别多样化患者的管理建议。
BJC Rep. 2023 Jun 22;1(1):1. doi: 10.1038/s44276-023-00002-0.
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Prevalence and predictors of cancer screening in transgender and gender nonbinary individuals.transgender和性别非二元个体中癌症筛查的患病率及预测因素
Int J Transgend Health. 2024 Jan 9;25(4):957-970. doi: 10.1080/26895269.2023.2294493. eCollection 2024.
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Breast care considerations for transgender and gender-diverse patients.跨性别和性别多样化患者的乳房保健注意事项。
Womens Health (Lond). 2024 Jan-Dec;20:17455057241289706. doi: 10.1177/17455057241289706.